CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival
about
PodocytesCapping protein regulators fine-tune actin assembly dynamicsThe function of endocytosis in podocytesSynaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturationStructure of the kidney slit diaphragm adapter protein CD2-associated protein as determined with electron microscopy.Yi qi qing re gao attenuates podocyte injury and inhibits vascular endothelial growth factor overexpression in puromycin aminonucleoside rat model.Reduction of proteinuria through podocyte alkalinization.The calcineurin-NFAT pathway allows for urokinase receptor-mediated beta3 integrin signaling to cause podocyte injury.Pathophysiology and treatment of focal segmental glomerulosclerosis: the role of animal models.Wtip- and gadd45a-interacting protein dendrin is not crucial for the development or maintenance of the glomerular filtration barrier.Whole-exome sequencing for the identification of susceptibility genes of Kashin-Beck diseaseReview series: The cell biology of renal filtration.Pathogenic pathways are activated in each major cell type of the glomerulus in the Cd2ap mutant mouse model of focal segmental glomerulosclerosisDendrin ablation prolongs life span by delaying kidney failure.Emerging role of autophagy in kidney function, diseases and agingSeptin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking.Modulators of sensitivity and resistance to inhibition of PI3K identified in a pharmacogenomic screen of the NCI-60 human tumor cell line collection.Podocyte-specific knockout of myosin 1e disrupts glomerular filtrationVitamin D receptor signaling in podocytes protects against diabetic nephropathy.Current concepts of the podocyte in nephrotic syndrome.The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity.Drug discovery in focal and segmental glomerulosclerosisA compendium of urinary biomarkers indicative of glomerular podocytopathy.FSGS3/CD2AP is a barbed-end capping protein that stabilizes actin and strengthens adherens junctions.Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal InjuryMolecular understanding of the slit diaphragm.The podocyte slit diaphragm--from a thin grey line to a complex signalling hub.Small molecule membrane transporters in the mammalian podocyte: a pathogenic and therapeutic target.Unwinding focal segmental glomerulosclerosisHeparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease.Human RAGE antibody protects against AGE-mediated podocyte dysfunction.A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD.CD2-associated protein regulates plasmacytoid dendritic cell migration, but is dispensable for their development and cytokine production.Interactions between Drosophila IgCAM adhesion receptors and cindr, the Cd2ap/Cin85 orthologaPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface.Is the antiproteinuric effect of cyclosporine a independent of its immunosuppressive function in T cells?Could Autophagic Exhaustion Be a Final Common Pathway for Podocytopathy in FSGS?Out-of-frame start codons prevent translation of truncated nucleo-cytosolic cathepsin L in vivo.CD2AP, dendrin, and cathepsin L in the kidney.
P2860
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P248
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P2860
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival
description
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Oktober 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/10/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/10/01)
@nl
наукова стаття, опублікована в жовтні 2011
@uk
مقالة علمية (نشرت في أكتوبر 2011)
@ar
name
CD2AP in mouse and human podoc ...... tructure and cellular survival
@ast
CD2AP in mouse and human podoc ...... tructure and cellular survival
@en
CD2AP in mouse and human podoc ...... tructure and cellular survival
@nl
type
label
CD2AP in mouse and human podoc ...... tructure and cellular survival
@ast
CD2AP in mouse and human podoc ...... tructure and cellular survival
@en
CD2AP in mouse and human podoc ...... tructure and cellular survival
@nl
prefLabel
CD2AP in mouse and human podoc ...... tructure and cellular survival
@ast
CD2AP in mouse and human podoc ...... tructure and cellular survival
@en
CD2AP in mouse and human podoc ...... tructure and cellular survival
@nl
P2093
P2860
P50
P921
P356
P1476
CD2AP in mouse and human podoc ...... tructure and cellular survival
@en
P2093
Andreas D. Kistler
Andrey S. Shaw
Anna-Lena Forst
Changkyu Gu
Changli Wei
Christian Faul
Clemens C. Möller
Isabel Fernandez
Jaakko Patrakka
Jan B. Flesche
P2860
P304
P356
10.1172/JCI58552
P407
P577
2011-10-01T00:00:00Z