Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
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The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responsesOsteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activityGrowth and repair factors, osteoactivin, matrix metalloproteinase and heat shock protein 72, increase with resolution of inflammation in musculotendinous tissues in a rat model of repetitive graspingMutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro.Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucomaExploratory study on the effect of osteoactivin on muscle regeneration in a rat volumetric muscle loss modelGlycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome-specific and proteolytically released protein.DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cellsIdentification of cell surface markers to differentiate rat endothelial and fibroblast cells using lectin arrays and LC-ESI-MS/MS.Dysregulation of gene expression in a lysosomal storage disease varies between brain regions implicating unexpected mechanisms of neuropathology.Depleting syndecan-4+ T lymphocytes using toxin-bearing dendritic cell-associated heparan sulfate proteoglycan-dependent integrin ligand: a new opportunity for treating activated T cell-driven diseaseTargeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice.Sézary syndrome cells overexpress syndecan-4 bearing distinct heparan sulfate moieties that suppress T-cell activation by binding DC-HIL and trapping TGF-beta on the cell surfaceAnalysis of the host transcriptome from demyelinating spinal cord of murine coronavirus-infected mice.Distinctive expression patterns of glycoprotein non-metastatic B and folliculin in renal tumors in patients with Birt-Hogg-Dubé syndrome.DC-HIL is a negative regulator of T lymphocyte activation.Glycoprotein Nonmetastatic Melanoma B (Gpnmb)-Positive Macrophages Contribute to the Balance between Fibrosis and Fibrolysis during the Repair of Acute Liver Injury in Mice.Mutation in Osteoactivin Promotes Receptor Activator of NFκB Ligand (RANKL)-mediated Osteoclast Differentiation and Survival but Inhibits Osteoclast FunctionComprehensive characterization of mesenchymal stem cells from human placenta and fetal membrane and their response to osteoactivin stimulation.Clinical significance of glycoprotein nonmetastatic B and its association with HER2 in breast cancer.Transgenic Expression of Osteoactivin/gpnmb Enhances Bone Formation In Vivo and Osteoprogenitor Differentiation Ex VivoThe Silver locus product Pmel17/gp100/Silv/ME20: controversial in name and in function.Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitisIn silico search for modifier genes associated with pancreatic and liver disease in Cystic FibrosisGlycoprotein non-metastatic b (GPNMB): A metastatic mediator and emerging therapeutic target in cancer.Osteoactivin (GPNMB) ectodomain protein promotes growth and invasive behavior of human lung cancer cells.Tumor-associated macrophages as incessant builders and destroyers of the cancer stroma.Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion.The novel monoclonal antibody 9F5 reveals expression of a fragment of GPNMB/osteoactivin processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain.A novel splice variant of Pmel17 expressed by human melanocytes and melanoma cells lacking some of the internal repeats.The DC-HIL/syndecan-4 pathway regulates autoimmune responses through myeloid-derived suppressor cells.Emerging therapeutic targets in breast cancer bone metastasis.High levels of FLT3-ligand in bone marrow and peripheral blood of patients with advanced multiple myeloma.Glycoprotein NMB: an Emerging Role in Neurodegenerative Disease.IL15RA is required for osteoblast function and bone mineralization.Knocking down glycoprotein nonmetastatic melanoma protein B suppresses the proliferation, migration, and invasion in bladder cancer cells.Osteoactivin Promotes Migration of Oral Squamous Cell Carcinomas.Prospects of osteoactivin in tissue regeneration.Osteoactivin promotes osteoblast adhesion through HSPG and αvβ1 integrin.Osteoactivin induces transdifferentiation of C2C12 myoblasts into osteoblasts.
P2860
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P2860
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
description
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Januar 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/01/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/01/01)
@nl
наукова стаття, опублікована в січні 2001
@uk
مقالة علمية (نشرت عام 2001)
@ar
name
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@ast
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@en
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@nl
type
label
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@ast
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@en
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@nl
prefLabel
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@ast
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@en
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@nl
P2093
P2860
P3181
P356
P1476
Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts
@en
P2093
F. F. Safadi
M. C. Rico
S. L. Smock
S. N. Popoff
T. A. Owen
P2860
P3181
P356
10.1002/JCB.1259
P577
2001-01-01T00:00:00Z