Transient receptor potential A1 mediates an osmotically activated ion channel
about
Deciphering Subtype-Selective Modulations in TRPA1 Biosensor ChannelsThe combinatorial nature of osmosensing in fishesTRPA1 as a drug target--promise and challengesTRP Channels in Skin Biology and PathophysiologyTRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed ratsTRPM8 is a neuronal osmosensor that regulates eye blinking in mice.En masse in vitro functional profiling of the axonal mechanosensitivity of sensory neuronsMechanosensory neurons, cutaneous mechanoreceptors, and putative mechanoproteins.The Met268Pro mutation of mouse TRPA1 changes the effect of caffeine from activation to suppressionMolecular basis determining inhibition/activation of nociceptive receptor TRPA1 protein: a single amino acid dictates species-specific actions of the most potent mammalian TRPA1 antagonist.Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.Ocular dryness excites two classes of corneal afferent neurons implicated in basal tearing in rats: involvement of transient receptor potential channels.Luminal hypertonicity and acidity modulate colorectal afferents and induce persistent visceral hypersensitivity.Quantitative characterization reveals three types of dry-sensitive corneal afferents: pattern of discharge, receptive field, and thermal and chemical sensitivity.Reciprocal effects of capsaicin and menthol on thermosensation through regulated activities of TRPV1 and TRPM8.1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1.TRPA1 regulates gastrointestinal motility through serotonin release from enterochromaffin cellsClioquinol and pyrithione activate TRPA1 by increasing intracellular Zn2+.Roles of transient receptor potential channels in pain.Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity.Recent advances in the biology and medicinal chemistry of TRPA1.The transient receptor potential channel TRPA1: from gene to pathophysiology.TRPs and pain.Ion channels involved in cold detection in mammals: TRP and non-TRP mechanisms.Identification of transmembrane domain 5 as a critical molecular determinant of menthol sensitivity in mammalian TRPA1 channels.The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1.Pore dilation occurs in TRPA1 but not in TRPM8 channels.Bimodal effects of cinnamaldehyde and camphor on mouse TRPA1.Transient receptor potential ankyrin 1 in spinal cord dorsal horn is involved in neuropathic pain in nerve root constriction ratsIdentification of molecular determinants for a potent mammalian TRPA1 antagonist by utilizing species differences.Requirement of extracellular Ca2+ binding to specific amino acids for heat-evoked activation of TRPA1.TRPA1 channel mediates organophosphate-induced delayed neuropathy.Heat and AITC activate green anole TRPA1 in a membrane-delimited manner.Hypotonicity-induced cell swelling activates TRPA1.
P2860
Q26786467-21C72634-914C-47D1-A39E-D48B2B0BD21EQ26823643-8C6B9753-0CDB-44D3-BA80-EC3A320033D0Q26863458-331DAFC9-CC5E-4CDA-902C-7F695C61F81AQ28066420-D291FD50-DBDF-470B-9C86-21B0CCD9D073Q28567323-20ED8041-7EBB-42FA-99E4-09CFBD8F877BQ30653067-1AAAB757-3455-4CA5-B0D5-BFAA201E78A9Q34136691-41988A1D-38E2-4461-AA58-C67F74178759Q34264627-76093281-0CB2-43CE-920B-63DD39F7C17AQ34388766-13CAECBB-9185-4925-831B-FBB85A7B7F35Q34509697-BBFA7EB9-3FA7-4235-9666-913FF1220734Q34720114-D16290EB-D858-4E76-841C-16B875B4C543Q35787569-83458BA2-9835-46C2-8EA7-6A2BF2AF9395Q36312362-282DD6D4-6161-4431-BAE5-05B27EC49E66Q36533284-A8417640-DB9F-441A-A828-7EB4DE830C17Q36577096-81B288CE-C460-4981-B9A5-C311DD8B3174Q36595632-D76F0104-4716-44F4-8B20-B1597FE9C893Q37117587-9564580C-8572-4E81-9FC6-DE4D4CE84D23Q37208534-A6AE9252-B27D-4AF2-960A-6180247761DFQ37388690-09715184-9632-4BD4-BE09-4AE92077C648Q37469275-8F7E8D71-A769-4859-9254-21995AD0EF86Q37855930-F1367B9A-B4D7-4D9C-BA16-DF4AC3981A4CQ38045749-D8F2F778-F51E-45CE-98D8-3F88401EC195Q38587736-E4A8B78F-B6B0-4FDA-8B25-F60E9A7FA327Q39310351-E2DA8B42-B09C-4988-94C3-5DBF4E582614Q39936129-DA33ECC5-6770-4291-B5E1-001AFECF9CB0Q41471829-973FFD0F-72D8-4A19-BD76-1AFB13877001Q42086231-1EE2FC24-2312-4338-A39B-6F7FFF36E3D4Q42518402-24D7F7E2-4FCC-46C4-8954-0506AF39A84EQ42833526-66020F0E-5BC6-42B2-BB99-74B2FAD6CDEBQ44675889-8CB771DA-A4AF-4C97-A96C-06A86311EA52Q48241862-F0DA2286-A6D6-474A-8D65-E09C9E332822Q50144366-34FAD346-6AD6-4AAC-B7ED-C59CD40E59CCQ50464619-B7FADED0-BF1D-415D-985E-39BFA903252FQ52765387-0E772ADA-3807-47C2-B1E2-B828B547558C
P2860
Transient receptor potential A1 mediates an osmotically activated ion channel
description
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Februar 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/02/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/02/01)
@nl
наукова стаття, опублікована в лютому 2008
@uk
مقالة علمية (نشرت في فبراير 2008)
@ar
name
Transient receptor potential A1 mediates an osmotically activated ion channel
@ast
Transient receptor potential A1 mediates an osmotically activated ion channel
@en
Transient receptor potential A1 mediates an osmotically activated ion channel
@nl
type
label
Transient receptor potential A1 mediates an osmotically activated ion channel
@ast
Transient receptor potential A1 mediates an osmotically activated ion channel
@en
Transient receptor potential A1 mediates an osmotically activated ion channel
@nl
prefLabel
Transient receptor potential A1 mediates an osmotically activated ion channel
@ast
Transient receptor potential A1 mediates an osmotically activated ion channel
@en
Transient receptor potential A1 mediates an osmotically activated ion channel
@nl
P2093
P2860
P921
P1476
Transient receptor potential A1 mediates an osmotically activated ion channel
@en
P2093
Connie R. Faltynek
Robert B. Moreland
Torben R. Neelands
Xu-Feng Zhang
P2860
P304
P356
10.1111/J.1460-9568.2008.06030.X
P407
P577
2008-02-01T00:00:00Z