A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
about
Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding.Tightening of the ATP-binding sites induces the opening of P2X receptor channelsGated access to the pore of a P2X receptor: structural implications for closed-open transitions.Regulation of ATP-gated P2X channels: from redox signaling to interactions with other proteinsCovalent modification of mutant rat P2X2 receptors with a thiol-reactive fluorophore allows channel activation by zinc or acidic pH without ATP.Activation and regulation of purinergic P2X receptor channelsOpposite effects of zinc on human and rat P2X2 receptors.New structure enlivens interest in P2X receptors.P2X receptors as drug targets.P2X receptor intermediate activation states have altered nucleotide selectivity.Dissecting the facilitator and inhibitor allosteric metal sites of the P2X4 receptor channel: critical roles of CYS132 for zinc potentiation and ASP138 for copper inhibition.
P2860
Q30371550-17F29CD5-F22D-4025-95DC-A38E01CA5E7BQ30513952-1B6BAB3C-B778-45B5-B920-D7F943FBF6C2Q33744436-6C39AC41-BE90-406A-948F-D24A670D821FQ33975173-9E1BC45C-B494-456E-9C1F-8E0AB879C730Q34462141-D62D1CD2-45B7-475E-B573-6A8013754AA5Q35122793-249B7DE8-FB7F-4871-B5E7-326315745632Q36982739-284ED5E5-0BEE-4DEB-A5EE-516E284429CEQ37708660-96648822-5663-4D99-991B-B3D5C93C7136Q38068620-7B70B625-37BA-4DC3-8EA9-601AA8CE41B4Q42604461-A0D5B056-1B28-4CB7-A5DB-F984844DE756Q46930619-2A47DD5C-0ACC-4772-B159-AA4C9A352835
P2860
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
description
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2007
@ast
im Juli 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/07/06)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/07/06)
@nl
наукова стаття, опублікована в липні 2007
@uk
name
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@ast
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@en
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@nl
type
label
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@ast
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@en
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@nl
prefLabel
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@ast
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@en
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@nl
P2093
P2860
P356
P1476
A histidine scan to probe the flexibility of the rat P2X2 receptor zinc-binding site
@en
P2093
Jamila M. Power
Rachel K. Tittle
Richard I. Hume
P2860
P304
19526–19533
P356
10.1074/JBC.M701604200
P407
P577
2007-07-06T00:00:00Z