Interleukin-1beta enhances nucleotide-induced and alpha-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y(2) receptor
about
Supportive or detrimental roles of P2Y receptors in brain pathology?--The two faces of P2Y receptors in stroke and neurodegeneration detected in neural cell and in animal model studiesPathophysiology of astroglial purinergic signallingP2Y2 nucleotide receptor-mediated responses in brain cells.Up-regulation and activation of the P2Y(2) nucleotide receptor mediate neurite extension in IL-1β-treated mouse primary cortical neuronsMagnesium ion influx reduces neuroinflammation in Aβ precursor protein/Presenilin 1 transgenic mice by suppressing the expression of interleukin-1β.P2Y receptors in Alzheimer's disease.P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential.Nucleotides released from Aβ₁₋₄₂ -treated microglial cells increase cell migration and Aβ₁₋₄₂ uptake through P2Y₂ receptor activationP2Y2 receptor transcription is increased by NF-kappa B and stimulates cyclooxygenase-2 expression and PGE2 released by intestinal epithelial cells.Purinergic receptors as potential therapeutic targets in Alzheimer's disease.Caveolin-1 Regulates the P2Y2 Receptor Signaling in Human 1321N1 Astrocytoma Cells.Loss of P2Y₂ nucleotide receptors enhances early pathology in the TgCRND8 mouse model of Alzheimer's disease.Emerging role of extracellular nucleotides and adenosine in multiple sclerosis.P2 receptors for extracellular nucleotides in the central nervous system: role of P2X7 and P2Y₂ receptor interactions in neuroinflammation.Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems.Neuroprotective roles of the P2Y(2) receptor.Review: experimental manipulations of microglia in mouse models of Alzheimer's pathology: activation reduces amyloid but hastens tau pathology.P2X and P2Y receptors—role in the pathophysiology of the nervous system.The Distinct Role of ADAM17 in APP Proteolysis and Microglial Activation Related to Alzheimer's Disease.Roles of extracellular nucleotides and P2 receptors in ectodomain shedding.Huperzine A alleviates synaptic deficits and modulates amyloidogenic and nonamyloidogenic pathways in APPswe/PS1dE9 transgenic mice.Opposite effects of P2X7 and P2Y2 nucleotide receptors on α-secretase-dependent APP processing in Neuro-2a cells.Potential role of IL-13 in neuroprotection and cortical excitability regulation in multiple sclerosis.The P2X7 Receptor in Inflammatory Diseases: Angel or Demon?The Metabotropic Purinergic P2Y Receptor Family as Novel Drug Target in Epilepsy.
P2860
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P2860
Interleukin-1beta enhances nucleotide-induced and alpha-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y(2) receptor
description
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
scientific journal article
@en
vedecký článok (publikovaný 2009/06/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/06/01)
@nl
наукова стаття, опублікована в червні 2009
@uk
مقالة علمية (نشرت في يونيو 2009)
@ar
name
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@ast
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@en
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@nl
type
label
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@ast
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@en
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@nl
prefLabel
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@ast
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@en
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@nl
P2093
P2860
P1476
Interleukin-1beta enhances nuc ...... ulation of the P2Y(2) receptor
@en
P2093
Agnes Simonyi
Cheikh I. Seye
Emily Stanley
Gary A. Weisman
Grace Y. Sun
Jean Camden
Laurie Erb
Olga Baker
Qiongman Kong
Troy S. Peterson
P2860
P304
P356
10.1111/J.1471-4159.2009.06048.X
P407
P577
2009-06-01T00:00:00Z