PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons
about
Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disordersNew pharmacological strategies for treatment of Alzheimer's disease: focus on disease modifying drugsRegulation of insulin degrading enzyme activity by obesity-associated factors and pioglitazone in liver of diet-induced obese miceType 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors.Withanolide A and asiatic acid modulate multiple targets associated with amyloid-beta precursor protein processing and amyloid-beta protein clearance.Ginsenoside Rg1 decreases Aβ(1-42) level by upregulating PPARγ and IDE expression in the hippocampus of a rat model of Alzheimer's disease.Green tea polyphenol epigallocatechin-3-gallate ameliorates insulin resistance in non-alcoholic fatty liver disease miceNotch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Aβ metabolismTranscriptional regulation of insulin-degrading enzyme modulates mitochondrial amyloid β (Aβ) peptide catabolism and functionality.Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice.Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor α.Neuroprotective mechanisms of peroxisome proliferator-activated receptor agonists in Alzheimer's disease.BRI2 protein regulates β-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE).Therapeutic potential of nuclear receptor agonists in Alzheimer's disease.Impact and Therapeutic Potential of PPARs in Alzheimer's Disease.Hyperglycemia induces the variations of 11β-hydroxysteroid dehydrogenase type 1 and peroxisome proliferator-activated receptor-γ expression in hippocampus and hypothalamus of diabetic rats.Effect of naringenin on brain insulin signaling and cognitive functions in ICV-STZ induced dementia model of rats.Sarsasapogenin suppresses Aβ overproduction induced by high glucose in HT-22 cells.Insulin degrading enzyme contributes to the pathology in a mixed model of Type 2 diabetes and Alzheimer's disease: possible mechanisms of IDE in T2D and AD.
P2860
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P2860
PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons
description
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Juni 2009 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2009/06/12)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/06/12)
@nl
наукова стаття, опублікована в червні 2009
@uk
مقالة علمية (نشرت في 12-6-2009)
@ar
name
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@ast
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@en
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@nl
type
label
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@ast
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@en
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@nl
prefLabel
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@ast
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@en
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@nl
P2093
P3181
P1476
PPARgamma transcriptionally re ...... ding enzyme in primary neurons
@en
P2093
Lang Zhang
Nanming Zhao
Xiuqing Huang
P304
P3181
P356
10.1016/J.BBRC.2009.04.047
P407
P577
2009-06-12T00:00:00Z