Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors - Wikidata - wikimedia - TriplyDB

Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors

Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors

http://www.wikidata.org/entity/Q28577465

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Ion Channels and Oxidative Stress as a Potential Link for the Diagnosis or Treatment of Liver Diseases MicroRNAs in the Cholangiopathies: Pathogenesis, Diagnosis, and Treatment Cilia in vertebrate development and disease Purinergic signalling in the gastrointestinal tract and related organs in health and disease Physiology of cholangiocytes Type 3 adenylyl cyclase: a key enzyme mediating the cAMP signaling in neuronal cilia Differentially expressed adenylyl cyclase isoforms mediate secretory functions in cholangiocyte subpopulation.Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease Impaired water reabsorption in mice deficient in the type VI adenylyl cyclase (AC6)Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases The cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel Function Aquaporin-1 facilitates angiogenic invasion in the pathological neovasculature that accompanies cirrhosis Cholangiocyte cilia are abnormal in syndromic and non-syndromic biliary atresia.Primary cilia-mediated mechanotransduction in human mesenchymal stem cells.Primary cilia respond to fluid shear stress and mediate flow-induced calcium deposition in osteoblasts.Advances in the pathogenesis and treatment of polycystic kidney disease Regulators of Cholangiocyte Proliferation.Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma.Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD.Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells.HDAC6 inhibition restores ciliary expression and decreases tumor growth Primary cilia are decreased in breast cancer: analysis of a collection of human breast cancer cell lines and tissues Polycystic kidney disease: inheritance, pathophysiology, prognosis, and treatment.Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia.Immortalized liver endothelial cells: a cell culture model for studies of motility and angiogenesis.The cAMP effectors Epac and protein kinase a (PKA) are involved in the hepatic cystogenesis of an animal model of autosomal recessive polycystic kidney disease (ARPKD).Patients, cells, and organelles: the intersection of science and serendipity.The role of cilia in the regulation of bile flow.SUMOylation regulates ciliary localization of olfactory signaling proteins.Coexpression of ecto-5'-nucleotidase/CD73 with specific NTPDases differentially regulates adenosine formation in the rat liver.Proteomics of Primary Cilia by Proximity Labeling Role of purinergic P2X receptors in the control of liver homeostasis.An intelligent nano-antenna: Primary cilium harnesses TRP channels to decode polymodal stimuli MicroRNAs in biliary diseases.Disruption of polycystin-L causes hippocampal and thalamocortical hyperexcitability Photoreceptor sensory cilia and ciliopathies: focus on CEP290, RPGR and their interacting proteins.Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling.Cholangiocyte proliferation and liver fibrosis.Autocrine regulation of biliary pathology by activated cholangiocytes.Adenylyl cyclase 3 haploinsufficiency confers susceptibility to diet-induced obesity and insulin resistance in mice.

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P2860

Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y12 purinergic receptors

http://www.wikidata.org/entity/Q28577465

description

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2008

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scientific journal article

@en

vedecký článok (publikovaný 2008/10/01)

@sk

vědecký článek publikovaný v roce 2008

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wetenschappelijk artikel (gepubliceerd op 2008/10/01)

@nl

наукова стаття, опублікована в жовтні 2008

@uk

مقالة علمية (نشرت في أكتوبر 2008)

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name

Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

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Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

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Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

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type

label

Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

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Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

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Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

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prefLabel

Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

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Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

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Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

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AJPGI.90265.2008

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American Journal of Physiology - Gastrointestinal and Liver Physiology

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Cholangiocyte primary cilia ar ...... via P2Y12 purinergic receptors

@en

P2093

Anatoliy I. Masyuk

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Angela J. Stroope

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Bing Q. Huang

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Jesus M. Banales

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Nicholas F. Larusso

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Patrick L. Splinter

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Sergio A. Gradilone

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Seung-Ok Lee

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Tatyana V. Masyuk

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P2860

ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999

Identification of the platelet ADP receptor targeted by antithrombotic drugs

Soluble adenylyl cyclase is localized to cilia and contributes to ciliary beat frequency regulation via production of cAMP

International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy

Radial spoke proteins of Chlamydomonas flagella

Cell physiology of cAMP sensor Epac.

Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice

Localization of extracellular matrix receptors on the chondrocyte primary cilium

Pharmacological profiles of cloned mammalian P2Y-receptor subtypes

Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1)

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G725–734

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3305099

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10.1152/AJPGI.90265.2008

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4

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295

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2008-10-01T00:00:00Z

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18687752

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2575915

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