85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
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Human and great ape red blood cells differ in plasmalogen levels and compositionBipolar disorder and mechanisms of action of mood stabilizersChronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E(2) concentration in rat brainChronic fluoxetine upregulates activity, protein and mRNA levels of cytosolic phospholipase A2 in rat frontal cortexDecrease in the AP-2 DNA-binding activity and in the protein expression of AP-2 alpha and AP-2 beta in frontal cortex of rats treated with lithium for 6 weeksDietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortexMood-stabilizers target the brain arachidonic acid cascade.Rat brain docosahexaenoic acid metabolism is not altered by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide.Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation.Chronic imipramine but not bupropion increases arachidonic acid signaling in rat brain: is this related to 'switching' in bipolar disorder?Novel insights into lithium's mechanism of action: neurotrophic and neuroprotective effectsPlasmalogens: workhorse lipids of membranes in normal and injured neurons and glia.Valproate uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: relevance to valproate's efficacy against bipolar disorderHigh throughput transcriptome profiling of lithium stimulated human mesenchymal stem cells reveals priming towards osteoblastic lineage.Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?Chronic olanzapine treatment decreases arachidonic acid turnover and prostaglandin E₂ concentration in rat brain.Lamotrigine blocks NMDA receptor-initiated arachidonic acid signalling in rat brain: implications for its efficacy in bipolar disorderImaging brain signal transduction and metabolism via arachidonic and docosahexaenoic acid in animals and humans.Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers.Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.Mood stabilizer psychopharmacologyGabapentin's minimal action on markers of rat brain arachidonic acid metabolism agrees with its inefficacy against bipolar disorder.Chronic carbamazepine administration reduces N-methyl-D-aspartate receptor-initiated signaling via arachidonic acid in rat brainEffects of chronic clozapine administration on markers of arachidonic acid cascade and synaptic integrity in rat brainChronic lithium feeding reduces upregulated brain arachidonic acid metabolism in HIV-1 transgenic rat.Aging is associated with altered inflammatory, arachidonic acid cascade, and synaptic markers, influenced by epigenetic modifications, in the human frontal cortex.Chronic carbamazepine administration attenuates dopamine D2-like receptor-initiated signaling via arachidonic acid in rat brain.Omega-3 polyunsaturated fatty acids for major depressive disorder.Potential application of lithium in Parkinson's and other neurodegenerative diseases.Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: a possible common effect of mood stabilizers.Chronic nutritional deprivation of n-3 alpha-linolenic acid does not affect n-6 arachidonic acid recycling within brain phospholipids of awake rats.Brain lipid metabolism in the cPLA2 knockout mouse.Chronic lithium administration to rats selectively modifies 5-HT2A/2C receptor-mediated brain signaling via arachidonic acid.Arachidonic acid incorporation and turnover is decreased in sympathetically denervated rat heart.Chronic lithium chloride administration to unanesthetized rats attenuates brain dopamine D2-like receptor-initiated signaling via arachidonic acid.Effect of chronic lithium administration on endothelium-dependent relaxation of rat mesenteric bed: role of nitric oxide.Chronic N-methyl-D-aspartate administration increases the turnover of arachidonic acid within brain phospholipids of the unanesthetized rat.Chronic NMDA administration to rats up-regulates frontal cortex cytosolic phospholipase A2 and its transcription factor, activator protein-2.Chronic fluoxetine increases cytosolic phospholipase A(2) activity and arachidonic acid turnover in brain phospholipids of the unanesthetized rat.Omega-3 fatty acid ethyl-eicosapentaenoate attenuates IL-1beta-induced changes in dopamine and metabolites in the shell of the nucleus accumbens: involved with PLA2 activity and corticosterone secretion.
P2860
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P2860
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
description
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
@ast
im Dezember 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/12/16)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/12/16)
@nl
наукова стаття, опублікована в грудні 1999
@uk
مقالة علمية نشرت في 16-12-1999 حول موضوع: دماغ
@ar
name
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@ast
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@en
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@nl
type
label
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@ast
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@en
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@nl
prefLabel
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@ast
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@en
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@nl
P2093
P1433
P1476
85 kDa cytosolic phospholipase A2 is a target for chronic lithium in rat brain
@en
P2093
J. Rintala
K. Chandrasekaran
M. A. Contreras
M. C. Chang
R. Seemann
S. I. Rapoport
T. A. Rosenberger
P304
P356
10.1097/00001756-199912160-00030
P577
1999-12-16T00:00:00Z