Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin
about
TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammalsNotch-Mediated Cell AdhesionNotch signaling as a novel regulator of metabolismDelta-Notch signalling in segmentationDirect observation of proteolytic cleavage at the S2 site upon forced unfolding of the Notch negative regulatory regionNotch1-Dll4 signalling and mechanical force regulate leader cell formation during collective cell migration.Mutational analysis of the Notch2 negative regulatory region identifies key structural elements for mechanical stability.Turn It Down a NotchNotch3 pathway alterations in ovarian cancer.Selective regulation of Notch ligands during angiogenesis is mediated by vimentinA mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2The modulation of cardiac progenitor cell function by hydrogel-dependent Notch1 activation.Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.Optical tweezers studies on Notch: single-molecule interaction strength is independent of ligand endocytosis.High-throughput optical screening of cellular mechanotransduction.The Biochemical Properties and Functions of CALM and AP180 in Clathrin Mediated Endocytosis.Inhibitors of endocytosis prevent Wnt/Wingless signalling by reducing the level of basal β-catenin/ArmadilloNo evidence for a functional role of bi-directional Notch signaling during angiogenesis.Cell signaling experiments driven by optical manipulationA glycosphingolipid binding domain controls trafficking and activity of the mammalian notch ligand delta-like 1Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization.CMV-induced embryonic mouse organ of corti dysplasia: Network architecture of dysfunctional lateral inhibition.Intramyocardial Delivery of Notch Ligand-Containing Hydrogels Improves Cardiac Function and Angiogenesis Following Infarction.Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth.High-throughput screening in niche-based assay identifies compounds to target preleukemic stem cells.Constructing modular and universal single molecule tension sensor using protein G to study mechano-sensitive receptors.Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.Defining Single Molecular Forces Required for Notch Activation Using Nano Yoyo.Growth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility.Targeting High Dynamin-2 (DNM2) Expression by Restoring Ikaros Function in Acute Lymphoblastic Leukemia.Membrane tethered delta activates notch and reveals a role for spatio-mechanical regulation of the signaling pathway.Notch, lipids, and endothelial cells.Ubiquitinations in the notch signaling pathway.Review series: From uncertain beginnings: initiation mechanisms of clathrin-mediated endocytosis.Endocytosis and signaling during developmentTherapeutic modulation of Notch signalling--are we there yet?Significance of glycosylation in Notch signaling.Confusing signals: recent progress in CTLA-4 biologyAsymmetric cell division in the Drosophila bristle lineage: from the polarization of sensory organ precursor cells to Notch-mediated binary fate decision.Lighting Up the Force: Investigating Mechanisms of Mechanotransduction Using Fluorescent Tension Probes.
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Notch ligand endocytosis generates mechanical pulling force dependent on dynamin, epsins, and actin
description
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im Juni 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/06/12)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/06/12)
@nl
наукова стаття, опублікована в червні 2012
@uk
مقالة علمية (نشرت في 12-6-2012)
@ar
name
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@ast
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@en
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@nl
type
label
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@ast
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@en
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@nl
prefLabel
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@ast
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@en
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@nl
P2093
P2860
P1433
P1476
Notch ligand endocytosis gener ...... on dynamin, epsins, and actin
@en
P2093
Bhupinder Shergill
Elliot Botvinick
Gerry Weinmaster
Laurence Meloty-Kapella
P2860
P304
P356
10.1016/J.DEVCEL.2012.04.005
P407
P577
2012-06-12T00:00:00Z