Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells
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Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell functionInternational Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors.Variants in MTNR1B influence fasting glucose levels.The role of melatonin in diabetes: therapeutic implicationsMelatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic isletsCatecholamines are the key for explaining the biological relevance of insulin-melatonin antagonisms in type 1 and type 2 diabetes.Minireview: Toward the establishment of a link between melatonin and glucose homeostasis: association of melatonin MT2 receptor variants with type 2 diabetes.Melatonin, energy metabolism, and obesity: a review.Understanding melatonin receptor pharmacology: latest insights from mouse models, and their relevance to human disease.MT2 receptors mediate the inhibitory effects of melatonin on nitric oxide-induced relaxation of porcine isolated coronary arteriesRole of melatonin on diabetes-related metabolic disorders.Melatonin Signaling Controls the Daily Rhythm in Blood Glucose Levels Independent of Peripheral ClocksMelatonin in aging and disease -multiple consequences of reduced secretion, options and limits of treatment.Melatonin and pancreatic islets: interrelationships between melatonin, insulin and glucagonImpact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology.Modulation by melatonin of the pathogenesis of inflammatory autoimmune diseases.Common genetic variation in the melatonin receptor 1B gene (MTNR1B) is associated with decreased early-phase insulin response.Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study.Genetic variants in MTNR1B affecting insulin secretion.Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling.Tired of diabetes genetics? Circadian rhythms and diabetes: the MTNR1B story?Experimental and clinical aspects of melatonin and clock genes in diabetes.Update on melatonin receptors: IUPHAR Review 20.Melatonin influences somatostatin secretion from human pancreatic δ-cells via MT1 and MT2 receptors.Chronomedicine and type 2 diabetes: shining some light on melatonin.Evidence of the receptor-mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein-coupled and PI3K signaling pathways.Phosphorylation of cyclic AMP-response element-binding protein (CREB) is influenced by melatonin treatment in pancreatic rat insulinoma β-cells (INS-1).Melatonin inhibits insulin secretion in rat insulinoma β-cells (INS-1) heterologously expressing the human melatonin receptor isoform MT2.Melatonin stimulates glucagon secretion in vitro and in vivo.The role of melatonin in the onset and progression of type 3 diabetes.Role of Neu-p11/luzindole in the regulation of insulin signaling pathways and insulin resistance.Melatonin supplementation therapy as a potent alternative to ERT in ovariectomized rats.The insulin-melatonin antagonism: studies in the LEW.1AR1-iddm rat (an animal model of human type 1 diabetes mellitus).Melatonin Uptake by Cells: An Answer to Its Relationship with Glucose?
P2860
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P2860
Involvement of the cGMP pathway in mediating the insulin-inhibitory effect of melatonin in pancreatic beta-cells
description
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im März 2008 veröffentlicher wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/10/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/10/01)
@nl
наукова стаття, опублікована в жовтні 2008
@uk
مقالة علمية (نشرت في أكتوبر 2008)
@ar
name
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@ast
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@en
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@nl
type
label
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@ast
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@en
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@nl
prefLabel
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@ast
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@en
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@nl
P1476
Involvement of the cGMP pathwa ...... tonin in pancreatic beta-cells
@en
P2093
Eckhard Mühlbauer
Ina Stumpf
P2860
P304
P356
10.1111/J.1600-079X.2008.00593.X
P577
2008-03-25T00:00:00Z