Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes
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Role of KLF15 in regulation of hepatic gluconeogenesis and metformin actionKnock-in Luciferase Reporter Mice for In Vivo Monitoring of CREB ActivityGlucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effectsCRTC3 links catecholamine signalling to energy balanceGs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP SignalingTargeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity.Transcriptional coregulators: fine-tuning metabolism.CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesisCREB and the CRTC co-activators: sensors for hormonal and metabolic signalsThe portal theory supported by venous drainage-selective fat transplantationGPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesityHepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2.Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity.Role of Pin1 protein in the pathogenesis of nonalcoholic steatohepatitis in a rodent modelcAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) promotes glucagon clearance and hepatic amino acid catabolism to regulate glucose homeostasis.Induction of cytosolic phospholipase a2α is required for adipose neutrophil infiltration and hepatic insulin resistance early in the course of high-fat feeding.Diet change and exercise enhance protein expression of CREB, CRTC 2 and lipolitic enzymes in adipocytes of obese miceNew aspects of gene-silencing for the treatment of cardiovascular diseasesFas (CD95) expression in myeloid cells promotes obesity‐induced muscle insulin resistance.CRTC2 enhances HBV transcription and replication by inducing PGC1α expression.Transcriptional regulators of hepatic gluconeogenesis.The New Biology and Pharmacology of Glucagon.Epigenomic and transcriptional control of insulin resistance.A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP-2.Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance.High sensitivity and label-free oligonucleotides detection using photonic bandgap sensing structures biofunctionalized with molecular beacon probes.Rose hip exerts antidiabetic effects via a mechanism involving downregulation of the hepatic lipogenic program.p300/CBP as a Key Nutritional Sensor for Hepatic Energy Homeostasis and Liver Fibrosis.
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P2860
Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes
description
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
scientific journal article
@en
vedecký článok (publikovaný 2009/11/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/11/01)
@nl
наукова стаття, опублікована в листопаді 2009
@uk
مقالة علمية (نشرت في نوفمبر 2009)
@ar
name
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@ast
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@en
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@nl
type
label
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@ast
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@en
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@nl
prefLabel
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@ast
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@en
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@nl
P2093
P2860
P3181
P1476
Novel liver-specific TORC2 siR ...... dent models of type 2 diabetes
@en
P2093
Barry Polisky
Chandra Vargeese
David Bjelica
Gautam Bandyopadhyay
Jerrold M Olefsky
Keith Bowman
Maziyar Saberi
Takeshi Imamura
Vasant Jadhar
Weimin Wang
P2860
P304
P3181
P356
10.1152/AJPENDO.00158.2009
P577
2009-08-25T00:00:00Z