Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy
about
Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human bloodStructural basis for Gas6-Axl signalling.GAS6-induced signaling in human endothelial cells is mediated by FOXO1aTyro3 family-mediated cell entry of Ebola and Marburg virusesDiscovery of Mer Specific Tyrosine Kinase Inhibitors for the Treatment and Prevention of ThrombosisElevated Serum Gas6 Is a Novel Prognostic Biomarker in Patients with Oral Squamous Cell Carcinoma.The Role of TAM Family Receptors in Immune Cell Function: Implications for Cancer TherapyThe Receptor Tyrosine Kinase AXL in Cancer ProgressionTargeting the TAM Receptors in LeukemiaRegulation of phagocytosis by Rho GTPasesTherapeutic approaches in arterial thrombosisPlasma levels of the growth arrest-specific gene 6 product (Gas6) and antiplatelet drug responsiveness in healthy subjectsAxl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migrationPlatelet-derived S100 family member myeloid-related protein-14 regulates thrombosis.Role of Gas6 in erythropoiesis and anemia in micePotentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilizationRGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase.A platelet tetraspanin superfamily member, CD151, is required for regulation of thrombus growth and stability in vivo.Endothelial cell specific adhesion molecule (ESAM) localizes to platelet-platelet contacts and regulates thrombus formation in vivoThe tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouse anorexia (anx) mutation.Immunobiology of the TAM receptors.Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα.Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets.RETRACTED: Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serumMinding the gaps to promote thrombus growth and stabilityDiannexin, an annexin A5 homodimer, binds phosphatidylserine with high affinity and is a potent inhibitor of platelet-mediated events during thrombus formation.Cross-phosphorylation, signaling and proliferative functions of the Tyro3 and Axl receptors in Rat2 cells.Axl as a mediator of cellular growth and survivalTAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer.Inhibition of Mer and Axl receptor tyrosine kinases in astrocytoma cells leads to increased apoptosis and improved chemosensitivity.Historical perspective and future directions in platelet research.A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation.Growth Arrest-Specific 6 (Gas6) and TAM Receptors in Mouse Platelets.TAM receptor signaling in immune homeostasis.The TAM-family receptor Mer mediates production of HGF through the RhoA-dependent pathway in response to apoptotic cellsStudy of Early Elevated Gas6 Plasma Level as a Predictor of Mortality in a Prospective Cohort of Patients with SepsisPlatelets in atherothrombosis: lessons from mouse models.The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrityLocalization and signaling of the receptor protein tyrosine kinase Tyro3 in cortical and hippocampal neurons.Growth arrest-specific gene 6 expression in human breast cancer.
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P2860
Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy
description
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Februar 2005 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2005/02/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/02/01)
@nl
наукова стаття, опублікована в лютому 2005
@uk
مقالة علمية (نشرت في فبراير 2005)
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name
Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
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Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
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Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
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type
label
Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
@ast
Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
@en
Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
@nl
prefLabel
Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
@ast
Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
@en
Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
@nl
P2093
P2860
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Role of Gas6 receptors in plat ...... ons for antithrombotic therapy
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Bernhard Wehrle-Haller
Christian Vesin
Désiré Collen
Edward M. Conway
Glenn K. Matsushima
Greg Lemke
H. Shelton Earp
Jean-Marc Herbert
Marc F. Hoylaerts
Maria DeMol
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P304
P3181
P356
10.1172/JCI200522079
10.1172/JCI22079
P407
P577
2005-02-01T00:00:00Z