The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
about
Overexpressed BCL6 (LAZ3) oncoprotein triggers apoptosis, delays S phase progression and associates with replication fociBCoR, a novel corepressor involved in BCL-6 repressionBCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphomaRegulation of BOB.1/OBF.1 stability by SIAHThe gene for interleukin-21 receptor is the partner of BCL6 in t(3;16)(q27;p11), which is recurrently observed in diffuse large B-cell lymphomaClass II histone deacetylases are directly recruited by BCL6 transcriptional repressorThe BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cellsAnalysis of BCL6-interacting proteins by tandem mass spectrometryBAZF, a novel Bcl6 homolog, functions as a transcriptional repressorThe human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: implications for a role of BCL6 in the down-regulation of apoptosisTranscriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switchingFollicular helper T cells in immunity and systemic autoimmunityFollicular helper T cells: lineage and locationLineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.The involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitisA Small-Molecule Inhibitor of BCL6 Kills DLBCL Cells In Vitro and In VivoThe ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domainHistone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyThe differential expression of IL-4 and IL-13 and its impact on type-2 immunityColocalization and heteromerization between the two human oncogene POZ/zinc finger proteins, LAZ3 (BCL6) and PLZFDefective T cell activation and autoimmune disorder in Stra13-deficient miceNon-immunoglobulin/BCL6 gene fusion in diffuse large B-cell lymphoma: prognostic implicationsBcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiationBcl6 mediates the development of T follicular helper cellsComponents of the SMRT corepressor complex exhibit distinctive interactions with the POZ domain oncoproteins PLZF, PLZF-RARalpha, and BCL-6Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasisDifferential gene expression between sensory neocortical areas: potential roles for Ten_m3 and Bcl6 in patterning visual and somatosensory pathwaysMutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systemsM17, a gene specific for germinal center (GC) B cells and a prognostic marker for GC B-cell lymphomas, is dispensable for the GC reaction in miceADAR1 protein induces adenosine-targeted DNA mutations in senescent Bcl6 gene-deficient cellsBCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targetsA negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiationRepression of an interleukin-4-responsive promoter requires cooperative BCL-6 functionA strategy for full interrogation of prognostic gene expression patterns: exploring the biology of diffuse large B cell lymphomaGeneration of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" miceImprinting the fate of antigen-reactive B cells through the affinity of the B cell receptor.The lupus-prone NZM2410/NZW strain-derived Sle1b sublocus alters the germinal center checkpoint in female mice in a B cell-intrinsic manner.Molecular definition of the germinal centre stage of B-cell differentiation.A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19(ARF)-p53 signaling.
P2860
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P2860
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
description
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 1997
@ast
im Juni 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/06/01)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/06/01)
@nl
наукова стаття, опублікована в червні 1997
@uk
name
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@ast
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@en
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@nl
type
label
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@ast
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@en
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@nl
prefLabel
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@ast
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@en
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@nl
P2093
P2860
P3181
P356
P1433
P1476
The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
@en
P2093
A. M. Stall
M. Nouri-Shirazi
P. Rothman
R. Dalla-Favera
P2860
P2888
P304
P3181
P356
10.1038/NG0697-161
P407
P577
1997-06-01T00:00:00Z
P5875
P6179
1047492526