Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis
about
NF-κB and STAT3 in glioblastoma: therapeutic targets coming of ageLoss-of-Function PTPRD Mutations Lead to Increased STAT3 Activation and Sensitivity to STAT3 Inhibition in Head and Neck CancerEvidence that homozygous PTPRD gene microdeletion causes trigonocephaly, hearing loss, and intellectual disability.PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetesGenomic Alteration in Head and Neck Squamous Cell Carcinoma (HNSCC) Cell Lines Inferred from Karyotyping, Molecular Cytogenetics, and Array Comparative Genomic Hybridization.Increased metastasis with loss of E2F2 in Myc-driven tumors.Identification of Copy Number Aberrations in Breast Cancer Subtypes Using Persistence Topology.The genetics of nodal marginal zone lymphomaGenetic variants in PTPRD and risk of gestational diabetes mellitus.Genetic alterations of protein tyrosine phosphatases in human cancers.Receptor-type protein tyrosine phosphatases in cancer.Genomic and Epigenomic Aberrations in Esophageal Squamous Cell Carcinoma and Implications for Patients.An epigenetic gateway to brain tumor cell identity.Recurrent epigenetic silencing of the PTPRD tumor suppressor in laryngeal squamous cell carcinoma.Role of STAT3 in Genesis and Progression of Human Malignant Gliomas.miR-135a-5p-mediated downregulation of protein tyrosine phosphatase receptor delta is a candidate driver of HCV-associated hepatocarcinogenesis.Clinical utility of recently identified diagnostic, prognostic, and predictive molecular biomarkers in mature B-cell neoplasms.Syndromic Craniosynostosis Can Define New Candidate Genes for Suture Development or Result from the Non-specifc Effects of Pleiotropic Genes: Rasopathies and Chromatinopathies as Examples.Protein tyrosine phosphatase receptor-type δ acts as a negative regulator suppressing breast cancer.The role of osmolarity adjusting agents in the regulation of encapsulated cell behavior to provide a safer and more predictable delivery of therapeutics.Protein tyrosine phosphatases receptor type D is a potential tumour suppressor gene inactivated by deoxyribonucleic acid methylation in paediatric acute myeloid leukaemia.Protein Tyrosine Phosphatases as Potential Regulators of STAT3 Signalingand Deleterious Mutations and Deletion Predict Bevacizumab Resistance in Metastatic Colorectal Cancer Patients
P2860
Q26830388-7A6E2CEB-EF50-48F1-A05A-DC197FC6E9B4Q27853197-D519B79C-52E6-4B4C-AFFD-5C60D36BDC95Q35747245-6AA78FAE-8980-4ECE-840B-F5460D4F9258Q35955186-9BC2F54E-F29C-4D22-9F58-F6EB9D8DE98EQ36097570-7CF9FC72-DA83-4F46-AB6F-B1904360EF46Q36545999-A4EF9DC8-D676-4EA1-8415-3B9D527D65BBQ37200784-4CB5E702-5F52-4F90-9110-AB661D602F98Q37243257-CC86087E-BA01-4990-87E2-F84EFA9B10F7Q37684508-64D82F7A-EED0-47E9-87A6-44902DF0B547Q38255066-F8C74EE7-24FE-4821-B6E7-E4BED68D9113Q38260826-EB19661E-D95F-498F-BA21-2639A113BE60Q38649673-A0C13358-1D81-408D-865B-3366CCE7D18CQ38682159-4441178A-279F-4E47-B9F4-28CA8FCEF03CQ38710424-2B1C6F96-E862-4D3C-B637-FCE74FA1F7B0Q38962315-98F87D98-C1D8-4D0D-8EBD-9D5BCD5C1316Q38979938-0FF5849C-5C4A-43AB-A57B-604733F5405CQ39406673-002A94C0-75EF-47DD-B113-55F2803EBAA6Q45423315-832744D9-D8C4-4E85-9406-731C6D28743EQ47152563-B910C295-092E-457E-B060-A74077C32AAAQ47701441-37242EDA-3E90-43FF-8193-38308C2E915FQ53269470-56F6AD35-9930-4B53-8B89-0E528DBA0C99Q58749617-A4584473-C3E4-4071-8E77-B5F9C9BAE954Q58761037-D879EC4F-6364-4C50-AF42-660EF309B03A
P2860
Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis
description
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2014
@ast
im Juni 2014 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2014/06/03)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/06/03)
@nl
наукова стаття, опублікована в червні 2014
@uk
name
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@ast
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@en
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@nl
type
label
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@ast
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@en
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@nl
prefLabel
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@ast
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@en
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@nl
P2093
P2860
P50
P3181
P356
P1476
Loss of the tyrosine phosphata ...... ion and promotes gliomagenesis
@en
P2093
Alicia Pedraza
Armida W M Fabius
Berenice Ortiz
Eric C Holland
Jacqueline F Bromberg
Jason T Huse
Timothy A Chan
P2860
P304
P3181
P356
10.1073/PNAS.1401952111
P407
P577
2014-06-03T00:00:00Z