Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity
about
The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases.Basophils and the T helper 2 environment can promote the development of lupus nephritis.Implications of population structure and ancestry on asthma genetic studies.A review of antisense therapeutic interventions for molecular biological targets in asthma.IgE regulates the expression of smMLCK in human airway smooth muscle cells.Src-family-tyrosine kinase Lyn is critical for TLR2-mediated NF-κB activation through the PI 3-kinase signaling pathway.Suppressor of cytokine signalling 1 (SOCS1) is a physiological regulator of the asthma responseBasophils and autoreactive IgE in the pathogenesis of systemic lupus erythematosus.Functions of the Lyn tyrosine kinase in health and diseaseSrc protein tyrosine kinase family and acute inflammatory responses.Susceptibility genes in severe asthma.Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.Case-control admixture mapping in Latino populations enriches for known asthma-associated genes.Src family kinases and lipid mediators in control of allergic inflammation.From bedside to bench to clinic trials: identifying new treatments for severe asthmaThe absence of Hck, Fgr, and Lyn tyrosine kinases augments lung innate immune responses to Pneumocystis murina.New insights on mast cell activation via the high affinity receptor for IgEA critical role for Lyn kinase in strengthening endothelial integrity and barrier function.Lyn mitigates mouse airway remodeling by downregulating the TGF-β3 isoform in house dust mite models.Lyn kinase controls basophil GATA-3 transcription factor expression and induction of Th2 cell differentiation.Multiple roles of Lyn kinase in myeloid cell signaling and function.SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophagesPharmacogenetics: implications of race and ethnicity on defining genetic profiles for personalized medicineLyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation.Basophils, IgE, and autoantibody-mediated kidney diseaseInternalization of B cell receptors in human EU12 μHC⁺ immature B cells specifically alters downstream signaling events.
P2860
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P2860
Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity
description
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im August 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/08/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/08/01)
@nl
наукова стаття, опублікована в серпні 2005
@uk
مقالة علمية (نشرت في أغسطس 2005)
@ar
name
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@ast
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@en
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@nl
type
label
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@ast
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@en
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@nl
prefLabel
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@ast
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@en
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@nl
P2093
P1476
Lyn-deficient mice develop sev ...... tive regulator of Th2 immunity
@en
P2093
Cathy Quilici
Debra Turner
Franca Casagranda
Gary P Anderson
Jessica Jones
Joanna M Kemp
Kenneth W Harder
Margaret L Hibbs
Peter D Sly
P304
P356
10.4049/JIMMUNOL.175.3.1867
P407
P577
2005-08-01T00:00:00Z