FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development
about
RAB23 mutations in Carpenter syndrome imply an unexpected role for hedgehog signaling in cranial-suture development and obesityCraniosynostosis in transgenic mice overexpressing Nell-1FGF9 can induce endochondral ossification in cranial mesenchyme.Fibroblast growth factor signaling in skeletal development and diseaseSignaling mechanisms implicated in cranial sutures pathophysiology: CraniosynostosisThe Hedgehog signalling pathway in bone formationYY1 activates Msx2 gene independent of bone morphogenetic protein signaling.FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesisGli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiationDisruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palateConcerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone developmentDevelopment of the turtle plastron, the order-defining skeletal structureSkeletal gene expression in the temporal region of the reptilian embryos: implications for the evolution of reptilian skull morphologyA bidirectional interface growth model for cranial interosseous suture morphogenesisDerivation of the mammalian skull vaultUnravelling the molecular control of calvarial suture fusion in children with craniosynostosis.Holoprosencephaly and craniosynostosis: A report of two siblings and review of the literatureEffects of growth hormone on the ontogenetic allometry of craniofacial bones.Paracrine interaction between adipose-derived stromal cells and cranial suture-derived mesenchymal cells.Strengthening molecular genetics and training in craniosynostosis: The need of the hour.Development of an efficient, non-viral transfection method for studying gene function and bone growth in human primary cranial suture mesenchymal cells reveals that the cells respond to BMP2 and BMP3.Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formationStructural basis for activation of fibroblast growth factor signaling by sucrose octasulfateRole of Indian hedgehog signaling in palatal osteogenesis.Effects of thyroxine exposure on osteogenesis in mouse calvarial pre-osteoblasts.A splicing switch and gain-of-function mutation in FgfR2-IIIc hemizygotes causes Apert/Pfeiffer-syndrome-like phenotypes.Human adipose-derived stromal cells stimulate autogenous skeletal repair via paracrine Hedgehog signaling with calvarial osteoblasts.Acute upregulation of hedgehog signaling in mice causes differential effects on cranial morphology.Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis.In vivo modulation of FGF biological activity alters cranial suture fateRole of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models.Decreased proliferation and altered differentiation in osteoblasts from genetically and clinically distinct craniosynostotic disorders.Prevention of premature fusion of calvarial suture in GLI-Kruppel family member 3 (Gli3)-deficient mice by removing one allele of Runt-related transcription factor 2 (Runx2).Additive effects of sonic hedgehog and Nell-1 signaling in osteogenic versus adipogenic differentiation of human adipose-derived stromal cells.Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development.Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts.Reduced bone morphogenetic protein receptor type 1A signaling in neural-crest-derived cells causes facial dysmorphism.ALX4 gain-of-function mutations in nonsyndromic craniosynostosisCommon mechanisms in development and disease: BMP signaling in craniofacial development.Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2.
P2860
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P2860
FGF-, BMP- and Shh-mediated signalling pathways in the regulation of cranial suture morphogenesis and calvarial bone development
description
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im April 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/04/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/04/01)
@nl
наукова стаття, опублікована у квітні 1998
@uk
مقالة علمية (نشرت في أبريل 1998)
@ar
name
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@ast
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@en
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@nl
type
label
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@ast
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@en
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@nl
prefLabel
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@ast
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@en
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@nl
P2093
P921
P3181
P1433
P1476
FGF-, BMP- and Shh-mediated si ...... and calvarial bone development
@en
P2093
D. P. Rice
I. Thesleff
P. J. Kettunen
P304
P3181
P407
P577
1998-04-01T00:00:00Z