p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
about
Strategies for developing novel therapeutics for sensorineural hearing loss.Gene expression analysis of forskolin treated basilar papillae identifies microRNA181a as a mediator of proliferation.Essential role of retinoblastoma protein in mammalian hair cell development and hearing.Quo vadis, hair cell regeneration?Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer.Rapid cell-cycle reentry and cell death after acute inactivation of the retinoblastoma gene product in postnatal cochlear hair cellsPostnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinasesThe Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner earGene therapy for the inner earThe genetics of hair cell development and regenerationMolecular mechanisms of inner ear developmentRegenerative medicine for the special senses: restoring the inputs.Sensory hair cell development and regeneration: similarities and differencesWhere hearing starts: the development of the mammalian cochleaCell cycle reactivation of cochlear progenitor cells in neonatal FUCCI mice by a GSK3 small molecule inhibitor.Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasionLGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea.Genomic analysis of the function of the transcription factor gata3 during development of the mammalian inner earDifferentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signalEarly transcriptional response to aminoglycoside antibiotic suggests alternate pathways leading to apoptosis in sensory hair cells in the mouse inner earCanal cristae growth and fiber extension to the outer hair cells of the mouse ear require Prox1 activityWnt5a functions in planar cell polarity regulation in mice.Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of CortiRegulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway.High-throughput screening reveals alsterpaullone, 2-cyanoethyl as a potent p27Kip1 transcriptional inhibitorp27Kip1 knockdown induces proliferation in the organ of Corti in culture after efficient shRNA lentiviral transductionHey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ developmentIn vivo genetic ablation of the periotic mesoderm affects cell proliferation survival and differentiation in the cochlea.A historical to present-day account of efforts to answer the question: "what puts the brakes on mammalian hair cell regeneration?"Curing hearing loss: Patient expectations, health care practitioners, and basic science.Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systemsIdentification of mouse cochlear progenitors that develop hair and supporting cells in the organ of CortiCharacterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea.In Vivo Interplay between p27Kip1, GATA3, ATOH1, and POU4F3 Converts Non-sensory Cells to Hair Cells in Adult Mice.Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.Mammalian Cochlear Hair Cell Regeneration and Ribbon Synapse ReformationBmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro.Protein phosphatase 2A promotes the transition to G0 during terminal differentiation in DrosophilaMEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear.Quantitative High-Resolution Cellular Map of the Organ of Corti.
P2860
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P2860
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
description
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
@ast
im April 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/04/01)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/04/01)
@nl
наукова стаття, опублікована у квітні 1999
@uk
مقالة علمية (نشرت في أبريل 1999)
@ar
name
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@ast
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@en
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@nl
type
label
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@ast
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@en
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@nl
prefLabel
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@ast
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@en
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@nl
P921
P3181
P1433
P1476
p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti
@en
P304
P3181
P407
P577
1999-04-01T00:00:00Z