Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones
about
A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc diseaseBone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junctionTGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and diseaseMolecular regulation of tendon cell fate during developmentTGF-β and BMP signaling in osteoblast differentiation and bone formationInteraction of TGFβ and BMP signaling pathways during chondrogenesisTGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissueTAK1 is an essential regulator of BMP signalling in cartilageIdentification of Chiari Type I Malformation subtypes using whole genome expression profiles and cranial base morphometricsMolecular profiling of the developing mouse axial skeleton: a role for Tgfbr2 in the development of the intervertebral disc.Smad signaling in skeletal development and regeneration.Erg cooperates with TGF-β to control mesenchymal differentiation.Smad7 regulates terminal maturation of chondrocytes in the growth plateTAK1 mediates BMP signaling in cartilage.Serine protease HTRA1 antagonizes transforming growth factor-β signaling by cleaving its receptors and loss of HTRA1 in vivo enhances bone formationSynovial joints: from development to homeostasis.TAK1 regulates cartilage and joint development via the MAPK and BMP signaling pathways.Genetic and functional studies of the intervertebral disc: a novel murine intervertebral disc modelTgfbr2 regulates the maintenance of boundaries in the axial skeleton.Insulin exerts direct, IGF-1 independent actions in growth plate chondrocytes.Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone developmentPDGF mediates TGFβ-induced migration during development of the spinous process.TGF-beta mediated Msx2 expression controls occipital somites-derived caudal region of skull development.TGF-beta signaling is essential for joint morphogenesis.The role of TGF-beta signaling in regulating chondrogenesis and osteogenesis during mandibular development.Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate.Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage.Biological treatment strategies for disc degeneration: potentials and shortcomings.TGF-beta type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling.Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signallingCritical roles of the TGF-beta type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate developmentTgfbr2 is required for development of the skull vault.Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation.TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages.A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development.Degeneration and regeneration of the intervertebral disc: lessons from development.Bridging the Gap: Understanding Embryonic Intervertebral Disc DevelopmentTGFβ signaling in cartilage development and maintenance.Coming together is a beginning: the making of an intervertebral disc.TGF-β signal transduction pathways and osteoarthritis.
P2860
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P2860
Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/01)
@nl
наукова стаття, опублікована в грудні 2004
@uk
مقالة علمية (نشرت في ديسمبر 2004)
@ar
name
Conditional deletion of the TG ...... onic development of long bones
@ast
Conditional deletion of the TG ...... onic development of long bones
@en
Conditional deletion of the TG ...... onic development of long bones
@nl
type
label
Conditional deletion of the TG ...... onic development of long bones
@ast
Conditional deletion of the TG ...... onic development of long bones
@en
Conditional deletion of the TG ...... onic development of long bones
@nl
prefLabel
Conditional deletion of the TG ...... onic development of long bones
@ast
Conditional deletion of the TG ...... onic development of long bones
@en
Conditional deletion of the TG ...... onic development of long bones
@nl
P2093
P3181
P1476
Conditional deletion of the TG ...... onic development of long bones
@en
P2093
Anna Chytil
Erin Slattery
Michael O. Baffi
Philip Sohn
Rosa Serra
P304
P3181
P356
10.1016/J.YDBIO.2004.08.027
P407
P577
2004-12-01T00:00:00Z