Early mitochondrial dysfunction in long-lived Mclk1+/- mice
about
Genetics and epigenetics of aging and longevityA regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegansCEP-1, the Caenorhabditis elegans p53 homolog, mediates opposing longevity outcomes in mitochondrial electron transport chain mutantsIdentification of the Target of the Retrograde Response that Mediates Replicative Lifespan Extension in Saccharomyces cerevisiaeMitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!The cell biology of agingHaploinsufficiency of akt1 prolongs the lifespan of miceReversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- miceAging and the Mammalian regulatory triumvirateLow abundance of the matrix arm of complex I in mitochondria predicts longevity in mice.Longevity pathways and memory agingAging: Dial M for MitochondriaLifelong protection from global cerebral ischemia and reperfusion in long-lived Mclk1(+/)(-) mutantsPerturbation of mitochondrial complex V alters the response to dietary restriction in DrosophilaWhen a theory of aging ages badly.Taking a "good" look at free radicals in the aging process.A mild impairment of mitochondrial electron transport has sex-specific effects on lifespan and aging in mice.Mitochondrial stress signaling in longevity: a new role for mitochondrial function in agingThe aging stress response.Mitochondrial oxidative stress alters a pathway in Caenorhabditis elegans strongly resembling that of bile acid biosynthesis and secretion in vertebrates.Mitochondrial-nuclear epistasis: implications for human aging and longevity.An enhanced immune response of Mclk1⁺/⁻ mutant mice is associated with partial protection from fibrosis, cancer and the development of biomarkers of aging.Aging: A mitochondrial DNA perspective, critical analysis and an update.The role of the mitochondrial genome in ageing and carcinogenesis.The role of mitochondria in Drosophila aging.Compensatory elevation of voluntary activity in mouse mutants with impaired mitochondrial energy metabolismInhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activityLower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity.The retrograde response: a conserved compensatory reaction to damage from within and from without.Collaboration between mitochondria and the nucleus is key to long life in Caenorhabditis elegans.Epithelial cell death is an important contributor to oxidant-mediated acute lung injury.Regulation of life span by mitochondrial respiration: the HIF-1 and ROS connection.Converging pathways in lifespan regulationMitochondrial and cytoplasmic ROS have opposing effects on lifespan.Inhibition of adenylyl cyclase type 5 increases longevity and healthful aging through oxidative stress protectionProteomic study of different culture medium serum volume fractions on RANKL-dependent RAW264.7 cells differentiating into osteoclastsMitochondria to nucleus signaling and the role of ceramide in its integration into the suite of cell quality control processes during agingMechanisms linking mtDNA damage and aging.The yeast retrograde response as a model of intracellular signaling of mitochondrial dysfunction.The retrograde response: when mitochondrial quality control is not enough
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P2860
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
description
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2008
@ast
im September 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/09/19)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/09/19)
@nl
наукова стаття, опублікована у вересні 2008
@uk
name
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@ast
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@en
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@nl
type
label
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@ast
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@en
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@nl
prefLabel
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@ast
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@en
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@nl
P2860
P3181
P356
P1476
Early mitochondrial dysfunction in long-lived Mclk1+/- mice
@en
P2093
Jérôme Lapointe
Siegfried Hekimi
P2860
P304
26217–26227
P3181
P356
10.1074/JBC.M803287200
P407
P577
2008-09-19T00:00:00Z