Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice
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Identification of a novel role for dematin in regulating red cell membrane function by modulating spectrin-actin interactionThe splicing regulator Rbfox2 is required for both cerebellar development and mature motor functionAdducin is involved in endothelial barrier stabilizationTropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeletonAnalysis of the mobilities of band 3 populations associated with ankyrin protein and junctional complexes in intact murine erythrocytes.Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane.Comparative proteomics reveals deficiency of SLC9A1 (sodium/hydrogen exchanger NHE1) in β-adducin null red cells.The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia.The membrane cytoskeletal protein adducin is phosphorylated by protein kinase C in D1 neurons of the nucleus accumbens and dorsal striatum following cocaine administration.Targeted deletion of the gamma-adducin gene (Add3) in mice reveals differences in alpha-adducin interactions in erythroid and nonerythroid cells.Analysis of novel sph (spherocytosis) alleles in mice reveals allele-specific loss of band 3 and adducin in alpha-spectrin-deficient red cells.Disclosing ambiguous gene aliases by automatic literature profilingThe malaria parasite progressively dismantles the host erythrocyte cytoskeleton for efficient egressSevere anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor.Adducins regulate remodeling of apical junctions in human epithelial cells.Sequence variation at multiple loci influences red cell hemoglobin concentration.Single-cell electrical lysis of erythrocytes detects deficiencies in the cytoskeletal protein networkGene map of large yellow croaker (Larimichthys crocea) provides insights into teleost genome evolution and conserved regions associated with growthAn α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegenerationStrain-specific hyperkyphosis and megaesophagus in Add1 null mice.The Actin-Binding Protein α-Adducin Is Required for Maintaining Axon Diameter.Gene disruption of dematin causes precipitous loss of erythrocyte membrane stability and severe hemolytic anemiaFeisty filaments: actin dynamics in the red blood cell membrane skeleton.Adducin forms a bridge between the erythrocyte membrane and its cytoskeleton and regulates membrane cohesion.Proteomic analysis of optic nerve lipid rafts reveals new paranodal proteins.Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types.Loss of the clock protein PER2 shortens the erythrocyte life span in mice.Antibody-mediated glycophorin C coligation on K562 cells induces phosphatidylserine exposure and cell death in an atypical apoptotic process.Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells.Erythrocyte adducin: a structural regulator of the red blood cell membrane.Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells.The neuronal and actin commitment: Why do neurons need rings?A Review on Adducin from Functional to Pathological Mechanisms: Future Direction in Cancer.The Regulation of Axon Diameter: From Axonal Circumferential Contractility to Activity-Dependent Axon Swelling
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P2860
Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice
description
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im November 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/11/15)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/11/15)
@nl
наукова стаття, опублікована в листопаді 2008
@uk
مقالة علمية (نشرت في 15-11-2008)
@ar
name
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@ast
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@en
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@nl
type
label
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@ast
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@en
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@nl
prefLabel
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@ast
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@en
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@nl
P2093
P2860
P1433
P1476
Targeted deletion of alpha-add ...... d lethal hydrocephalus in mice
@en
P2093
Babette Gwynn
Diana M. Gilligan
Kenneth E. Sahr
Luanne L. Peters
Raymond F. Robledo
Steven L. Ciciotte
P2860
P304
P356
10.1182/BLOOD-2008-05-156000
P407
P577
2008-11-15T00:00:00Z