UBF levels determine the number of active ribosomal RNA genes in mammals
about
Morphology of nuclear transcriptionNucleolar dysfunction in Huntington's diseaseBasic mechanisms in RNA polymerase I transcription of the ribosomal RNA genesPerturbations at the ribosomal genes loci are at the centre of cellular dysfunction and human diseaseA cell cycle role for the epigenetic factor CTCF-L/BORISGenetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae.Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progressionInhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signalingInvolvement of a novel preimplantation-specific gene encoding the high mobility group box protein Hmgpi in early embryonic developmentInhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53PICT-1 triggers a pro-death autophagy through inhibiting rRNA transcription and AKT/mTOR/p70S6K signaling pathway.Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcriptionNucleolin is required for DNA methylation state and the expression of rRNA gene variants in Arabidopsis thalianaHistone H1 phosphorylation is associated with transcription by RNA polymerases I and IIThe chromatin remodelling complex B-WICH changes the chromatin structure and recruits histone acetyl-transferases to active rRNA genes.Methylation of histone H3 and H4 by PRMT5 regulates ribosomal RNA gene transcription.Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease.Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor bodyA novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes.The HBx oncoprotein of hepatitis B virus potentiates cell transformation by inducing c-Myc-dependent expression of the RNA polymerase I transcription factor UBFWisely chosen paths--regulation of rRNA synthesis: delivered on 30 June 2010 at the 35th FEBS Congress in Gothenburg, Sweden.CTCF regulates the local epigenetic state of ribosomal DNA repeats.Dysregulation of RNA polymerase I transcription during disease.Analysis of human protein replacement stable cell lines established using snoMEN-PR vectorc-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiationIntegrative genomic analysis of human ribosomal DNA.Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells.Glycogen synthase kinase (GSK) 3β phosphorylates and protects nuclear myosin 1c from proteasome-mediated degradation to activate rDNA transcription in early G1 cells.Proteomic characterization of the nucleolar linker histone H1 interaction network.RNA polymerase I activity is regulated at multiple steps in the transcription cycle: recent insights into factors that influence transcription elongation.Genome wide mapping of UBF binding-sites in mouse and human cell lines.The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positionsWnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I.Construction of synthetic nucleoli and what it tells us about propagation of sub-nuclear domains through cell division.Analysis of histone modifications at human ribosomal DNA in liver cancer cellDepletion of the cisplatin targeted HMGB-box factor UBF selectively induces p53-independent apoptotic death in transformed cells.Old drug, new target: ellipticines selectively inhibit RNA polymerase I transcription.Ribosomal RNA gene transcription mediated by the master genome regulator protein CCCTC-binding factor (CTCF) is negatively regulated by the condensin complex.Serum starvation-induced cell cycle synchronization stimulated mouse rDNA transcription reactivation during somatic cell reprogramming into iPSCsThe histone demethylase JMJD2A/KDM4A links ribosomal RNA transcription to nutrients and growth factors availability.
P2860
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P2860
UBF levels determine the number of active ribosomal RNA genes in mammals
description
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Dezember 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/12/29)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/12/29)
@nl
наукова стаття, опублікована в грудні 2008
@uk
مقالة علمية (نشرت في 29-12-2008)
@ar
name
UBF levels determine the number of active ribosomal RNA genes in mammals
@ast
UBF levels determine the number of active ribosomal RNA genes in mammals
@en
UBF levels determine the number of active ribosomal RNA genes in mammals
@nl
type
label
UBF levels determine the number of active ribosomal RNA genes in mammals
@ast
UBF levels determine the number of active ribosomal RNA genes in mammals
@en
UBF levels determine the number of active ribosomal RNA genes in mammals
@nl
prefLabel
UBF levels determine the number of active ribosomal RNA genes in mammals
@ast
UBF levels determine the number of active ribosomal RNA genes in mammals
@en
UBF levels determine the number of active ribosomal RNA genes in mammals
@nl
P2093
P2860
P50
P3181
P356
P1476
UBF levels determine the number of active ribosomal RNA genes in mammals
@en
P2093
Elysia Robb
Grant A. McArthur
Katherine M. Hannan
Kerith Sharkey
Lawrence Rothblum
Richard B. Pearson
Ross D. Hannan
Timothy P. Holloway
Victor Stefanovsky
P2860
P304
P3181
P356
10.1083/JCB.200805146
P407
P577
2008-12-29T00:00:00Z