Interferon-ε protects the female reproductive tract from viral and bacterial infection
about
Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responsesRegulation of type I interferon responsesExpansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversityInterferons and viruses: an evolutionary arms race of molecular interactionsAntiviral regulation in porcine monocytic cells at different activation statesContraction of the type I IFN locus and unusual constitutive expression of IFN-α in batsInterferon induction and function at the mucosal surface.Estrous cycle stage-dependent manner of type I interferon-stimulated genes induction in the bovine endometriumInterferons, signal transduction pathways, and the central nervous system.An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survivalUnraveling the convoluted biological roles of type I interferons in infection and immunity: a way forward for therapeutics and vaccine design.Type I interferons in bacterial infections: taming of myeloid cells and possible implications for autoimmunity.Molecular evolution of the porcine type I interferon family: subtype-specific expression and antiviral activity.The mucosal expression pattern of interferon-ε in rhesus macaquesUse of a Guinea pig-specific transcriptome array for evaluation of protective immunity against genital chlamydial infection following intranasal vaccination in Guinea pigs.Vaginal microbiota and its role in HIV transmission and infection.IFN-ε is constitutively expressed by cells of the reproductive tract and is inefficiently secreted by fibroblasts and cell lines.Evasion of early antiviral responses by herpes simplex viruses.Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus InfectionHIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1Interferon Kappa Inhibits Human Papillomavirus 31 Transcription by Inducing Sp100 ProteinsThe role of sex hormones in immune protection of the female reproductive tract.HIV-1-negative female sex workers sustain high cervical IFNɛ, low immune activation, and low expression of HIV-1-required host genes17β-Estradiol inhibits HIV-1 by inducing a complex formation between β-catenin and estrogen receptor α on the HIV promoter to suppress HIV transcription.Novel role for molecular transporter importin 9 in posttranscriptional regulation of IFN-ε expressionPangolin genomes and the evolution of mammalian scales and immunity.IFN-ε protects primary macrophages against HIV infectionMolecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.Type I interferons regulate susceptibility to inflammation-induced preterm birth.ISG15 in the tumorigenesis and treatment of cancer: An emerging role in malignancies of the digestive system.Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma.Tumor necrosis factor-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease.Ovarian steroid hormones: effects on immune responses and Chlamydia trachomatis infections of the female genital tract.Modulation of autoimmune rheumatic diseases by oestrogen and progesterone.Interferon epsilon promotes HIV restriction at multiple steps of viral replication.Type-I-interferons in infection and cancer: Unanticipated dynamics with therapeutic implications.Transcriptional Profiling of Human Endocervical Tissues Reveals Distinct Gene Expression in the Follicular and Luteal Phases of the Menstrual Cycle.TLR4 Signaling Is a Major Mediator of the Female Tract Response to Seminal Fluid in Mice.Human Immunodeficiency Virus 1 and Type I Interferons-Where Sex Makes a DifferenceDifferential regulation of IFNα, IFNβ and IFNε gene expression in human cervical epithelial cells.
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P2860
Interferon-ε protects the female reproductive tract from viral and bacterial infection
description
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2013
@ast
im März 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/03/01)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/03/01)
@nl
наукова стаття, опублікована в березні 2013
@uk
name
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@ast
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@en
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@nl
type
label
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@ast
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@en
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@nl
prefLabel
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@ast
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@en
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Interferon-ε protects the female reproductive tract from viral and bacterial infection
@en
P2093
Daniel J Carr
Helen Cumming
Hong P T Nguyen
Jay C Horvat
Jemma R Mayall
Ka Yee Fung
Philip M Hansbro
Sebastian A Stifter
P2860
P304
P3181
P356
10.1126/SCIENCE.1233321
P407
P50
P577
2013-03-01T00:00:00Z