Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
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Ectopic mineralization in the middle ear and chronic otitis media with effusion caused by RPL38 deficiency in the Tail-short (Ts) mouse.Otitis media in a new mouse model for CHARGE syndrome with a deletion in the Chd7 geneMouse models for human otitis mediaThe mouse ascending: perspectives for human-disease modelsIncreased susceptibility to otitis media in a Splunc1-deficient mouse modelEya4-deficient mice are a model for heritable otitis media.Mcph1-deficient mice reveal a role for MCPH1 in otitis mediaEvaluation of 15 functional candidate genes for association with chronic otitis media with effusion and/or recurrent otitis media (COME/ROM).Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.Tympanometry assessment of 61 inbred strains of mice.Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3.Mutations in MECOM, Encoding Oncoprotein EVI1, Cause Radioulnar Synostosis with Amegakaryocytic ThrombocytopeniaHIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.The transcriptome of a complete episode of acute otitis mediaExome sequencing identifies a missense mutation in Isl1 associated with low penetrance otitis media in dearisch miceEVI1 acts as an inducible negative-feedback regulator of NF-κB by inhibiting p65 acetylation.Panel 3: Genetics and Precision Medicine of Otitis Media.Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung.Mouse models for the study of mucosal vaccination against otitis media.Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutantNutritional factors in the pathogenesis of ear disease in children: a systematic review.Ectodysplasin signalling deficiency in mouse models of hypohidrotic ectodermal dysplasia leads to middle ear and nasal pathology.Unraveling the genetics of otitis media: from mouse to human and back again.Genetic susceptibility to otitis media in childhood.Mouse models of otitis media: strengths and limitations.Panel 1: Epidemiology, natural history, and risk factors.What have we learned from murine models of otitis media?The role of vascular endothelial growth factor and vascular stability in diseases of the ear.Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015).Myringotomy in the Junbo mouse model of chronic otitis media alleviates inflammation and cellular hypoxia.Non-Typeable Haemophilus influenzae Infection of the Junbo Mouse.A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse.A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways.A mouse-to-man candidate gene study identifies association of chronic otitis media with the loci TGIF1 and FBXO11A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment.FBXO11, a regulator of the TGFβ pathway, is associated with severe otitis media in Western Australian children.Upgrading mouse health and welfare: direct benefits of a large-scale rederivation programme.Understanding the aetiology and resolution of chronic otitis media from animal and human studies.Loss of the homeostatic protein BPIFA1, leads to exacerbation of otitis media severity in the Junbo mouse model.
P2860
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P2860
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
description
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
scientific journal article
@en
vedecký článok (publikovaný 2006/10/06)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/10/06)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в жовтні 2006
@uk
مقالة علمية (نشرت في 6-10-2006)
@ar
name
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@ast
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@en
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@nl
type
label
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@ast
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@en
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@nl
prefLabel
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@ast
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@en
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@nl
P2093
P2860
P3181
P1433
P1476
Mutation at the Evi1 locus in Junbo mice causes susceptibility to otitis media
@en
P2093
A. Jackie Hunter
Anne-Marie Woodward
Debra Brooker
Francesca MacKenzie
Hilda Tateossian
Hsun-Tien Tsai
Ivana Barbaric
Martin Fray
Michael T. Cheeseman
P2860
P3181
P356
10.1371/JOURNAL.PGEN.0020149
P577
2006-10-06T00:00:00Z