IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses
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Development, migration, and survival of mast cellsRole of ABCC1 in export of sphingosine-1-phosphate from mast cellsThe immunosuppressant drug FTY720 inhibits cytosolic phospholipase A2 independently of sphingosine-1-phosphate receptorsSphingolipids and Epoxidized Lipid Metabolites in the Control of Gut Immunosurveillance and AllergyLipid Mediators of Allergic Disease: Pathways, Treatments, and Emerging Therapeutic TargetsPhospholipid scramblase 1 modulates a selected set of IgE receptor-mediated mast cell responses through LAT-dependent pathwaySphingosine kinase 1Molecular mechanisms of spontaneous and directed mast cell motility.Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema.Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice.Involvement of Fc receptors in disorders of the central nervous system.Extracellular and intracellular actions of sphingosine-1-phosphateRegulation of Ca2+ signaling with particular focus on mast cells.Distinct roles of sphingosine kinases 1 and 2 in human mast-cell functions.Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration"Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets.Loss of TRPC1-mediated Ca2+ influx contributes to impaired degranulation in Fyn-deficient mouse bone marrow-derived mast cellsAn emerging role for the lipid mediator sphingosine-1-phosphate in mast cell effector function and allergic disease.Sphingosine-1-phosphate induces development of functionally mature chymase-expressing human mast cells from hematopoietic progenitors.Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells.BACE1 activity is modulated by cell-associated sphingosine-1-phosphate.The outs and the ins of sphingosine-1-phosphate in immunityRegulation of mast cell responses in health and disease.Sphingosine-1-phosphate in allergic responses, asthma and anaphylaxis.G protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation.Signal transduction and chemotaxis in mast cellsSphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell functionShaping the landscape: metabolic regulation of S1P gradients.The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function.Inducible IL-33 expression by mast cells is regulated by a calcium-dependent pathway.Phospholipids: "greasing the wheels" of humoral immunityA specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthmaUsage of sphingosine kinase isoforms in mast cells is species and/or cell type determined.Interrogation of sphingosine-1-phosphate receptor 2 function in vivo reveals a prominent role in the recovery from IgE and IgG-mediated anaphylaxis with minimal effect on its onsetUnraveling the complexities of sphingosine-1-phosphate function: the mast cell model.Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling.The Vibrio cholerae cytolysin promotes activation of mast cell (T helper 2) cytokine productionThe alliance of sphingosine-1-phosphate and its receptors in immunity.The role of sphingosine-1-phosphate and its receptors in asthma.A lipid binding domain in sphingosine kinase 2
P2860
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P2860
IgE-dependent activation of sphingosine kinases 1 and 2 and secretion of sphingosine 1-phosphate requires Fyn kinase and contributes to mast cell responses
description
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2006
@ast
im Februar 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/02/03)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/02/03)
@nl
наукова стаття, опублікована в лютому 2006
@uk
name
IgE-dependent activation of sp ...... ributes to mast cell responses
@ast
IgE-dependent activation of sp ...... ributes to mast cell responses
@en
IgE-dependent activation of sp ...... ributes to mast cell responses
@nl
type
label
IgE-dependent activation of sp ...... ributes to mast cell responses
@ast
IgE-dependent activation of sp ...... ributes to mast cell responses
@en
IgE-dependent activation of sp ...... ributes to mast cell responses
@nl
prefLabel
IgE-dependent activation of sp ...... ributes to mast cell responses
@ast
IgE-dependent activation of sp ...... ributes to mast cell responses
@en
IgE-dependent activation of sp ...... ributes to mast cell responses
@nl
P2093
P921
P356
P1476
IgE-dependent activation of sp ...... ributes to mast cell responses
@en
P2093
Alasdair M Gilfillan
Ana Olivera
Juan Rivera
Kiyomi Mizugishi
Nicole Urtz
Thomas Baumruker
Yasuko Furumoto
Yumi Yamashita
P304
P356
10.1074/JBC.M508931200
P407
P577
2005-11-29T00:00:00Z