Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis
about
The dynamic cilium in human diseasesA complex of BBS1 and NPHP7 is required for cilia motility in zebrafishExome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signalingCandidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathyIndividuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathyNEK8 mutations affect ciliary and centrosomal localization and may cause nephronophthisisDCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signalingNephronophthisisGli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal diseaseMechanisms of nephronophthisis and related ciliopathiesSpectrum of clinical diseases caused by disorders of primary ciliaNephronophthisis-associated CEP164 regulates cell cycle progression, apoptosis and epithelial-to-mesenchymal transitionIdentification of a plant isoflavonoid that causes biliary atresiaMouse models of ciliopathies: the state of the art.The nonmotile ciliopathies.A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.Nephronophthisis and related syndromesMultiprotein complexes of Retinitis Pigmentosa GTPase regulator (RPGR), a ciliary protein mutated in X-linked Retinitis Pigmentosa (XLRP).Mutation of the Mg2+ transporter SLC41A1 results in a nephronophthisis-like phenotypeImpaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathyThe Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcriptionKruppel-like zinc finger protein Glis2 is essential for the maintenance of normal renal functionsIdentification of nuclear localization, DNA binding, and transactivating mechanisms of Kruppel-like zinc finger protein Gli-similar 2 (Glis2)Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programsCiliopathiesPolycystic kidney disease in the medaka (Oryzias latipes) pc mutant caused by a mutation in the Gli-Similar3 (glis3) gene.Characterization of the tandem CWCH2 sequence motif: a hallmark of inter-zinc finger interactionsNephronophthisis: disease mechanisms of a ciliopathy.Genotype-phenotype correlation in 440 patients with NPHP-related ciliopathiesLights on for aminopeptidases in cystic kidney disease.Polycystic kidney disease.Partial uniparental isodisomy of chromosome 16 unmasks a deleterious biallelic mutation in IFT140 that causes Mainzer-Saldino syndrome.Genetic kidney diseases.Mutations in ANKS6 cause a nephronophthisis-like phenotype with ESRD.microRNA biomarkers in cystic diseases.Clinical characterization and NPHP1 mutations in nephronophthisis and associated ciliopathies: a single center experience.Ciliopathies: the trafficking connection.Downregulating hedgehog signaling reduces renal cystogenic potential of mouse modelsA new Cre driver mouse line, Tcf21/Pod1-Cre, targets metanephric mesenchymeRenal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling
P2860
Q21202039-6BF10109-3A17-410E-98F6-466E0B23FE7EQ21558497-CA3D3CC6-E8E5-41DF-A4F9-CF274EDDC273Q24294774-B62DC5A4-5343-448B-80C6-DB7A88DD01C9Q24299464-415B834C-D83A-45C6-BE16-E83174F26188Q24300810-3F24E3B9-7618-44C8-8E0C-112E9D8AD2E1Q24306642-454349B6-F5AB-4DE0-844E-090E3DB0AFAAQ24311957-53B7357D-FCBA-4B91-8177-9BA498068902Q24601139-A2A98EA7-8DC6-4BD4-ADBD-0083F21ED3E1Q24631284-3AA28E1D-DC1B-4FA8-B87A-56217428EA4CQ24634201-816AEDB5-3D10-45C2-B25B-ADA2A6C209E0Q27024881-4FD4C8BC-CE8B-4BD8-B4FD-7D8784A698E4Q27313602-AD32201F-C0F2-4897-86B6-6565ABD476F0Q27325798-7A7BD680-A038-4FF3-AA85-268740CA4C97Q27692039-D9DAC007-1560-4F2E-9EB8-E134C8451848Q27967648-251BC389-E69E-4B61-AB91-A1AFDA84C78FQ28000057-EC25D7BB-6C53-4E52-A607-BE3EE4C89E9EQ28081939-BEFD4594-A925-4404-8D91-FFBD89992BBDQ28114957-31DECA36-F23D-4B4C-A292-A0CAC32ECACEQ28115060-3ABF90B9-931B-4720-8774-6136C2C32646Q28506100-AFFA93BC-87E8-49EC-897C-C3B73832393CQ28507859-95C1543D-759C-47EB-B75D-CA3910A5AB6EQ28511036-CA9F4DFE-BC02-490F-938B-0396F07AF585Q28513862-582DC3CC-3988-4AAE-9BC8-CD224710C18BQ28588215-34A952A0-CF26-4F54-80D6-B269D20EE6FDQ29614821-F3FBF8E9-E223-427B-94AC-2D917D59CFD8Q33483340-0455E462-7542-4E6A-AF62-6BD0608C828CQ33532316-0EDA3B23-80D3-49C7-BB3F-D2CEF7DFA205Q33594278-9CA95DFD-BB0D-49BD-82CF-A3A15077F8EAQ33682550-963C1B80-07EA-4C68-B9E7-67A2E19B0B3DQ33685714-374F36F1-83A1-43D0-A436-F18E1F1BE627Q33709685-A1FCF1E7-A65A-497B-8126-2397E95089FFQ33919216-BF469146-1EBC-45ED-8E10-8D771BD921B4Q33968487-8F6E8772-188B-49AE-AA4E-26DFB5738F43Q33974574-DC0452CE-6E63-45E1-9B62-AD26BB726AEDQ34049572-D76F74F2-AF9E-4199-ACCA-83A6CABF5441Q34133175-E3040B1C-4586-4773-A5E8-E3FA447BF2D7Q34207085-E2D50121-A12A-4C96-B62B-2020D4830604Q34260011-164944F5-3B9C-4CF0-AA79-3FAEFAC0BA99Q34336506-9DBBD2BE-E9F9-451A-B217-F9E63E2A925FQ34427583-DB382268-6735-4926-9FB7-F7076F5414D1
P2860
Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis
description
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2007
@ast
im August 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/08/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/08/01)
@nl
наукова стаття, опублікована в серпні 2007
@uk
name
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@ast
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@en
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@nl
type
label
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@ast
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@en
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@nl
prefLabel
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@ast
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@en
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@nl
P2093
P50
P356
P1433
P1476
Loss of GLIS2 causes nephronop ...... creased apoptosis and fibrosis
@en
P2093
Albert E. Chudley
Anna-Corina Treier
Christian Becker
Claudia Klugmann
John A. Sayer
John F. O'Toole
Juliana Helou
Katrin Anlag
Mathias Treier
N. Henriette Uhlenhaut
P2888
P304
P356
10.1038/NG2072
P407
P577
2007-08-01T00:00:00Z