Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction
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Searching for new targets for treatment of pediatric epilepsyCortical HCN channels: function, trafficking and plasticityStructure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channelsTemperature affects voltage-sensitive conductances differentially in octopus cells of the mammalian cochlear nucleusTrafficking and surface expression of hyperpolarization-activated cyclic nucleotide-gated channels in hippocampal neuronsPostnatal development of dendritic synaptic integration in rat neocortical pyramidal neuronsColocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cellsLocalization of HCN1 channels to presynaptic compartments: novel plasticity that may contribute to hippocampal maturationIdentification of Small-Molecule Inhibitors of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels.Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.Mislocalization of h channel subunits underlies h channelopathy in temporal lobe epilepsy.Reduction of thalamic and cortical Ih by deletion of TRIP8b produces a mouse model of human absence epilepsy.K+ channel regulator KCR1 suppresses heart rhythm by modulating the pacemaker current If.TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels.Dendritic ion channel trafficking and plasticity.Regulated expression of HCN channels and cAMP levels shape the properties of the h current in developing rat hippocampusRegulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.Reelin signaling specifies the molecular identity of the pyramidal neuron distal dendritic compartment.Targeted deletion of Kcne2 impairs HCN channel function in mouse thalamocortical circuits.Dynamic measurements for funny channels.Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease.Dendritic Na(+) spikes enable cortical input to drive action potential output from hippocampal CA2 pyramidal neurons.HCN channels in behavior and neurological disease: too hyper or not active enough?Mechanisms and function of dendritic exocytosis.Quantitative analysis and subcellular distribution of mRNA and protein expression of the hyperpolarization-activated cyclic nucleotide-gated channels throughout development in rat hippocampus.A di-arginine ER retention signal regulates trafficking of HCN1 channels from the early secretory pathway to the plasma membrane.Trafficking and gating of hyperpolarization-activated cyclic nucleotide-gated channels are regulated by interaction with tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) and cyclic AMP at distinct sites.Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent mannerTRIP8b is required for maximal expression of HCN1 in the mouse retinaLocalization and function of Ih channels in a small neural network.The fast and slow ups and downs of HCN channel regulation.Corticospinal-specific HCN expression in mouse motor cortex: I(h)-dependent synaptic integration as a candidate microcircuit mechanism involved in motor controlHCN channelopathies: pathophysiology in genetic epilepsy and therapeutic implicationsAn N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities.Dorsoventral differences in intrinsic properties in developing CA1 pyramidal cells.Impaired dendritic expression and plasticity of h-channels in the fmr1(-/y) mouse model of fragile X syndrome.Differential dorso-ventral distributions of Kv4.2 and HCN proteins confer distinct integrative properties to hippocampal CA1 pyramidal cell distal dendrites.Augmented currents of an HCN2 variant in patients with febrile seizure syndromesRegulation of gating and rundown of HCN hyperpolarization-activated channels by exogenous and endogenous PIP2
P2860
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P248
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P2860
Regulation of HCN channel surface expression by a novel C-terminal protein-protein interaction
description
2004 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im November 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/11/24)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/11/24)
@nl
наукова стаття, опублікована в листопаді 2004
@uk
مقالة علمية (نشرت في 24-11-2004)
@ar
name
Regulation of HCN channel surf ...... al protein-protein interaction
@ast
Regulation of HCN channel surf ...... al protein-protein interaction
@en
Regulation of HCN channel surf ...... al protein-protein interaction
@nl
type
label
Regulation of HCN channel surf ...... al protein-protein interaction
@ast
Regulation of HCN channel surf ...... al protein-protein interaction
@en
Regulation of HCN channel surf ...... al protein-protein interaction
@nl
prefLabel
Regulation of HCN channel surf ...... al protein-protein interaction
@ast
Regulation of HCN channel surf ...... al protein-protein interaction
@en
Regulation of HCN channel surf ...... al protein-protein interaction
@nl
P2093
P921
P1476
Regulation of HCN channel surf ...... al protein-protein interaction
@en
P2093
Bina Santoro
Brian J Wainger
Steven A Siegelbaum
P304
10750-10762
P356
10.1523/JNEUROSCI.3300-04.2004
P407
P577
2004-11-01T00:00:00Z