Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene
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Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitroαβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunctionIncreased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synucleinSevere vestibular dysfunction and altered vestibular innervation in mice lacking prosaposinLocalization of synucleins in the mammalian cochleaGamma-synucleinopathy: neurodegeneration associated with overexpression of the mouse protein.Myelination transition zone astrocytes are constitutively phagocytic and have synuclein dependent reactivity in glaucoma.Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins.Gene expression profiling of two distinct neuronal populations in the rodent spinal cord.Absence of alpha-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice.Lipid classes and fatty acid patterns are altered in the brain of γ-synuclein null mutant mice.Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis.Differential involvement of the gamma-synuclein in cognitive abilities on the model of knockout mice.Gamma-synuclein pathology in amyotrophic lateral sclerosisDirect membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein.γ-Synuclein antibodies have neuroprotective potential on neuroretinal cells via proteins of the mitochondrial apoptosis pathway.Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family.Evaluation of the synuclein-γ (SNCG) gene as a PPARγ target in murine adipocytes, dorsal root ganglia somatosensory neurons, and human adipose tissue.Gamma-synuclein is an adipocyte-neuron gene coordinately expressed with leptin and increased in human obesity.Hunk/Mak-v is a negative regulator of intestinal cell proliferationDimebon slows progression of proteinopathy in γ-synuclein transgenic mice.Increased lipolysis and altered lipid homeostasis protect γ-synuclein-null mutant mice from diet-induced obesity.Contrasting effects of α-synuclein and γ-synuclein on the phenotype of cysteine string protein α (CSPα) null mutant mice suggest distinct function of these proteins in neuronal synapses.Targets of tyrosine nitration in diabetic rat retina.Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice.γ-synuclein is a novel player in the control of body lipid metabolism.Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism.Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly.α-Synuclein promotes dilation of the exocytotic fusion pore.Differential expression of sarcoplasmic and myofibrillar proteins of rat soleus muscle during denervation atrophy.Whole genome expression analyses of single- and double-knock-out mice implicate partially overlapping functions of alpha- and gamma-synuclein.Effect of gamma-synuclein silencing on apoptotic pathways in retinal ganglion cells.Characterization of three synuclein genes in Xenopus laevis.
P2860
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P2860
Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene
description
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im November 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/11/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/11/01)
@nl
наукова стаття, опублікована в листопаді 2003
@uk
مقالة علمية (نشرت في نوفمبر 2003)
@ar
name
Neurons expressing the highest ...... geted inactivation of the gene
@ast
Neurons expressing the highest ...... geted inactivation of the gene
@en
Neurons expressing the highest ...... geted inactivation of the gene
@nl
type
label
Neurons expressing the highest ...... geted inactivation of the gene
@ast
Neurons expressing the highest ...... geted inactivation of the gene
@en
Neurons expressing the highest ...... geted inactivation of the gene
@nl
prefLabel
Neurons expressing the highest ...... geted inactivation of the gene
@ast
Neurons expressing the highest ...... geted inactivation of the gene
@en
Neurons expressing the highest ...... geted inactivation of the gene
@nl
P2093
P2860
P3181
P1476
Neurons expressing the highest ...... geted inactivation of the gene
@en
P2093
Alun M. Davies
Arnon Rosenthal
Darren C. Robertson
Felipe Court
Francis O'Neill
Katerina Papachroni
Liz Delaney
Natalia Ninkina
Oliver Schmidt
Susan M. Fleetwood-Walker
P2860
P304
P3181
P356
10.1128/MCB.23.22.8233-8245.2003
P407
P577
2003-11-01T00:00:00Z