Type 3 deiodinase is critical for the maturation and function of the thyroid axis.
about
Cellular and molecular basis of deiodinase-regulated thyroid hormone signalingHypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in ratsDeiodinases: implications of the local control of thyroid hormone actionScope and limitations of iodothyronine deiodinases in hypothyroidismInherited defects in thyroid hormone cell-membrane transport and metabolismThe syndromes of reduced sensitivity to thyroid hormoneSelenoproteins in nervous system development and functionMinireview: the role of nuclear receptors in photoreceptor differentiation and diseaseType 3 deiodinase: role in cancer growth, stemness, and metabolismThyroid hormone and the developing hypothalamusThe thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretionType 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptorsAn evo-devo approach to thyroid hormones in cerebral and cerebellar cortical development: etiological implications for autismRole of maternal thyroid hormones in the developing neocortex and during human evolutionThyroid hormone receptors control developmental maturation of the middle ear and the size of the ossicular bonesA protective role for type 3 deiodinase, a thyroid hormone-inactivating enzyme, in cochlear development and auditory function.Embryonic exposure to excess thyroid hormone causes thyrotrope cell deathAt least ten genes define the imprinted Dlk1-Dio3 cluster on mouse chromosome 12qF1Deciphering direct and indirect influence of thyroid hormone with mouse genetics.The 5'-deiodinases are not essential for the fasting-induced decrease in circulating thyroid hormone levels in male mice: possible roles for the type 3 deiodinase and tissue sequestration of hormoneMaternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic β-cells and disrupts glucose homeostasis.IL-6 promotes nonthyroidal illness syndrome by blocking thyroxine activation while promoting thyroid hormone inactivation in human cellsHalogenated phenolic contaminants inhibit the in vitro activity of the thyroid-regulating deiodinases in human liverLife without the iodothyronine deiodinases.Mice with hepatocyte-specific deficiency of type 3 deiodinase have intact liver regeneration and accelerated recovery from nonthyroidal illness after toxin-induced hepatonecrosis.The imprinted gene DIO3 is a candidate gene for litter size in pigs.Intrinsic expression of a multiexon type 3 deiodinase gene controls zebrafish embryo sizeType 3 deiodinase deficiency causes spatial and temporal alterations in brain T3 signaling that are dissociated from serum thyroid hormone levelsA novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neuronsGenomic imprinting variations in the mouse type 3 deiodinase gene between tissues and brain regions.The role of genomic imprinting in biology and disease: an expanding view.Thyroid hormone function in the rat testis.Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism.Reawakened interest in type III iodothyronine deiodinase in critical illness and injury.Minireview: Defining the roles of the iodothyronine deiodinases: current concepts and challengesThe selective loss of the type 2 iodothyronine deiodinase in mouse thyrotrophs increases basal TSH but blunts the thyrotropin response to hypothyroidism.The role of imprinted genes in fetal growth abnormalities.Hypothyroidism and brain developmental players.Thyroid-specific inactivation of KIF3A alters the TSH signaling pathway and leads to hypothyroidism.The Correlation between Polybrominated Diphenyl Ethers (PBDEs) and Thyroid Hormones in the General Population: A Meta-Analysis.
P2860
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P2860
Type 3 deiodinase is critical for the maturation and function of the thyroid axis.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Type 3 deiodinase is critical for the maturation and function of the thyroid axis
@nl
Type 3 deiodinase is critical for the maturation and function of the thyroid axis.
@ast
Type 3 deiodinase is critical for the maturation and function of the thyroid axis.
@en
type
label
Type 3 deiodinase is critical for the maturation and function of the thyroid axis
@nl
Type 3 deiodinase is critical for the maturation and function of the thyroid axis.
@ast
Type 3 deiodinase is critical for the maturation and function of the thyroid axis.
@en
prefLabel
Type 3 deiodinase is critical for the maturation and function of the thyroid axis
@nl
Type 3 deiodinase is critical for the maturation and function of the thyroid axis.
@ast
Type 3 deiodinase is critical for the maturation and function of the thyroid axis.
@en
P2093
P2860
P356
P1476
Type 3 deiodinase is critical for the maturation and function of the thyroid axis.
@en
P2093
Arturo Hernandez
Donald St Germain
M Elena Martinez
Steven Fiering
Valerie Anne Galton
P2860
P304
P356
10.1172/JCI26240
P407
P577
2006-01-12T00:00:00Z