Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity
about
RACK1, A multifaceted scaffolding protein: Structure and function.Testin interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice.RACK-1 regulates let-7 microRNA expression and terminal cell differentiation in Caenorhabditis elegans.Overexpressions of RACK1 and CD147 associated with poor prognosis in stage T1 pulmonary adenocarcinoma.Nkd1 functions as a passive antagonist of Wnt signaling.Planar cell polarity aligns osteoblast division in response to substrate strainDisc1 regulates both β-catenin-mediated and noncanonical Wnt signaling during vertebrate embryogenesis.A dynamic intracellular distribution of Vangl2 accompanies cell polarization during zebrafish gastrulationSignaling in cell differentiation and morphogenesisHair cell BK channels interact with RACK1, and PKC increases its expression on the cell surface by indirect phosphorylation.MicroRNA-206 regulates cell movements during zebrafish gastrulation by targeting prickle1a and regulating c-Jun N-terminal kinase 2 phosphorylation.Secreted and transmembrane wnt inhibitors and activators.Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear.Van-Gogh-like 2 antagonises the canonical WNT pathway and is methylated in colorectal cancersReceptor for Activated C Kinase 1 (RACK1) Promotes Dishevelled Protein Degradation via Autophagy and Antagonizes Wnt SignalingNovel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway.Planar cell polarity signaling: coordination of cellular orientation across tissues.Planar cell polarity of the kidney.PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling.Receptor for activated C kinase 1 (RACK1) inhibits function of transient receptor potential (TRP)-type channel Pkd2L1 through physical interaction.RACK1 is involved in endothelial barrier regulation via its two novel interacting partnersSpina bifida-predisposing heterozygous mutations in Planar Cell Polarity genes and Zic2 reduce bone mass in young mice.Rack1 function in intestinal epithelia: regulating crypt cell proliferation and regeneration and promoting differentiation and apoptosis.FZD6 encoding the Wnt receptor frizzled 6 is mutated in autosomal-recessive nail dysplasia.Trafficking, localization and degradation of the Na+,HCO3- co-transporter NBCn1 in kidney and breast epithelial cells.TMEM59 potentiates Wnt signaling by promoting signalosome formation.
P2860
Q30407898-CC028B16-7A25-4184-9ED3-2C8BAF46B8D9Q31136145-9851CF5F-F8F6-48D5-86BF-7C8DEAB536ADQ33953160-39F5DDAF-4DF1-4405-9C98-3374EA0E3001Q34271830-8ABA70B3-95EF-476F-8985-6F9FAC5CF8BDQ34979880-CBB7C13B-70F7-43B8-BC7D-5740D535E236Q35097037-967EBC4E-1E47-464C-99CF-ADAD51102212Q35609628-91306980-B5EA-4F1C-AC15-B583E5C3D839Q35878114-919F987A-9035-4135-94B2-90C0066867CEQ36009264-83DED54A-F4BA-4692-ACF2-C34760E997D3Q36114652-FBF0AFC0-32BC-4264-8274-4F906B0E8CDDQ36155067-1901F27A-3AD4-45E9-90E3-FB760A86DCA2Q36626700-D527B262-C776-4BD0-809D-2C31919B253AQ36815071-054EB8F7-3AE8-4672-A534-95609C2EAFFBQ36889627-BF281A20-AD5B-4E56-8A34-029FD77F00F5Q37066543-ACD95925-5758-4292-AC69-5F2E1D73EFEAQ37619275-46B70D7A-D6D4-4798-8C18-43C11EC2EBEDQ38052130-11049529-EDC4-49CF-9153-EF3C77721025Q38274898-A561C2CC-8F56-44DC-A6B3-0BC060E9FF9EQ38441808-16829C05-E04B-40AF-A542-2B02976CF73CQ41888133-398637FF-962E-4C18-B908-FEF9A2F7FCBCQ42074120-92187BB0-E771-40E9-9EF7-DF7EAC803CEFQ49789426-6363C1D3-ADAE-4657-B2CD-44467CCAFC1AQ49953677-C6099E1F-354D-4559-9A4E-18441C8FE4EEQ51829567-EA17C17A-1061-4CA6-9F14-F0DB782BF2EBQ55129594-CD1D9FFD-F302-4FE1-A38C-04F3DAC1521DQ55403164-F9571415-7812-4D1C-80EB-E59693E05DE4
P2860
Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity
description
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2011
@ast
im Februar 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/02/08)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/02/08)
@nl
наукова стаття, опублікована в лютому 2011
@uk
name
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@ast
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@en
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@nl
type
label
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@ast
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@en
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@nl
prefLabel
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@ast
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@en
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@nl
P2093
P2860
P356
P1476
Rack1 is required for Vangl2 m ...... nuating canonical Wnt activity
@en
P2093
Andreas Fritz
Dongdong Ren
Fanglu Chi
Jean-Luc Parent
Kristen Radde-Gallwitz
Robert Esterberg
Shuangding Li
Veronik Lachance
P2860
P304
P356
10.1073/PNAS.1013170108
P407
P577
2011-02-08T00:00:00Z