Dosage-sensitive requirement for mouse Dll4 in artery development
about
Angiogenic factors stimulate growth of adult neural stem cellsThree-dimensional analysis of vascular development in the mouse embryoBotch promotes neurogenesis by antagonizing NotchCerebral cavernous malformation protein CCM1 inhibits sprouting angiogenesis by activating DELTA-NOTCH signaling.Targeting neural precursors in the adult brain rescues injured dopamine neuronsDelta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sproutingTargeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapyCoordinating tissue interactions: Notch signaling in cardiac development and diseaseImpact of notch signaling on inflammatory responses in cardiovascular disordersNotch: a key regulator of tumor angiogenesis and metastasisContext-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations.FOXO3 promotes quiescence in adult muscle stem cells during the process of self-renewalEndothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle developmentBiodistribution and toxicity of pegylated single wall carbon nanotubes in pregnant mice.Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesisDosage-dependent requirement for mouse Vezf1 in vascular system developmentContext-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In VivoOverexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryosVascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesisEssential role of endothelial Notch1 in angiogenesisDll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cellsMind bomb-2 is an E3 ligase for Notch ligandNotch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signallingThe Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expressionConditionals by inversion provide a universal method for the generation of conditional allelesArterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signalingMultiscale models of angiogenesisElongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sproutingNotch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants.Automated discovery of tissue-targeting enhancers and transcription factors from binding motif and gene function data.An obligatory role of mind bomb-1 in notch signaling of mammalian developmentTNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotypeMind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells.Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli.KSHV manipulates Notch signaling by DLL4 and JAG1 to alter cell cycle genes in lymphatic endotheliaEffects of varying Notch1 signal strength on embryogenesis and vasculogenesis in compound mutant heterozygotes.Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cellsLunatic Fringe-mediated Notch signaling is required for lung alveogenesis.KSHV-induced notch components render endothelial and mural cell characteristics and cell survival.
P2860
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P2860
Dosage-sensitive requirement for mouse Dll4 in artery development
description
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Oktober 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/10/15)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/10/15)
@nl
наукова стаття, опублікована в жовтні 2004
@uk
مقالة علمية (نشرت في 15-10-2004)
@ar
name
Dosage-sensitive requirement for mouse Dll4 in artery development
@ast
Dosage-sensitive requirement for mouse Dll4 in artery development
@en
Dosage-sensitive requirement for mouse Dll4 in artery development
@nl
type
label
Dosage-sensitive requirement for mouse Dll4 in artery development
@ast
Dosage-sensitive requirement for mouse Dll4 in artery development
@en
Dosage-sensitive requirement for mouse Dll4 in artery development
@nl
prefLabel
Dosage-sensitive requirement for mouse Dll4 in artery development
@ast
Dosage-sensitive requirement for mouse Dll4 in artery development
@en
Dosage-sensitive requirement for mouse Dll4 in artery development
@nl
P2860
P50
P3181
P356
P1433
P1476
Dosage-sensitive requirement for mouse Dll4 in artery development
@en
P2093
Luís Costa
Masanori Hirashima
P2860
P304
P3181
P356
10.1101/GAD.1239004
P50
P577
2004-10-15T00:00:00Z