Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse
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Responses to Microbial Challenges by SLAMF ReceptorsReceptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complexSignaling lymphocyte activation molecule regulates development of colitis in miceNK cell cytotoxicity mediated by 2B4 and NTB-A is dependent on SAP acting downstream of receptor phosphorylation.Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategySystems-level analysis of innate immunity.Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors.SLAMF4 Is a Negative Regulator of Expansion of Cytotoxic Intraepithelial CD8+ T Cells That Maintains Homeostasis in the Small IntestineTight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral loadInhibition of Donor-Reactive CD8+ T Cell Responses by Selective CD28 Blockade Is Independent of Reduced ICOS Expression.Tyrosine kinase Btk is required for NK cell activationMerck Ad5/HIV induces broad innate immune activation that predicts CD8⁺ T-cell responses but is attenuated by preexisting Ad5 immunity.Roles of CD48 in regulating immunity and tolerance.2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses.EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization.T Cell Cosignaling Molecules in Transplantation.A combination of an anti-SLAMF6 antibody and ibrutinib efficiently abrogates expansion of chronic lymphocytic leukemia cellsGut symbiotic microbes imprint intestinal immune cells with the innate receptor SLAMF4 which contributes to gut immune protection against enteric pathogens.Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling.Prevention of graft-versus-host disease by adoptive T regulatory therapy is associated with active repression of peripheral blood Toll-like receptor 5 mRNA expression.
P2860
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P2860
Cutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouse
description
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im November 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/11/15)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/11/15)
@nl
наукова стаття, опублікована в листопаді 2010
@uk
مقالة علمية (نشرت في 15-11-2010)
@ar
name
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@ast
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@en
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@nl
type
label
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@ast
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@en
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@nl
prefLabel
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@ast
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@en
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@nl
P2093
P2860
P921
P3181
P356
P1476
Cutting edge: The adapters EAT ...... functions in the C57BL/6 mouse
@en
P2093
Chunyan Ma
Cox Terhorst
Jill Westcott
John D Schatzle
Ninghai Wang
Silvia Calpe
Wilson Castro
P2860
P304
P3181
P356
10.4049/JIMMUNOL.1001974
P407
P50
P577
2010-10-20T00:00:00Z