NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
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Emerging preclinical pharmacological targets for Parkinson's diseaseNeuroprotective Transcription Factors in Animal Models of Parkinson DiseaseMaintenance of postmitotic neuronal cell identityPhosphodiesterase 7 inhibition preserves dopaminergic neurons in cellular and rodent models of Parkinson diseaseAging and luteinizing hormone effects on reactive oxygen species production and DNA damage in rat Leydig cells.Research resource: nuclear receptors as transcriptome: discriminant and prognostic value in breast cancerProstaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strengthRasd1 modulates the coactivator function of NonO in the cyclic AMP pathway.Profile of microRNAs following rat sciatic nerve injury by deep sequencing: implication for mechanisms of nerve regeneration.The role of histone acetylation in memory formation and cognitive impairments.α-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons.Nuclear receptors in neurodegenerative diseases.Early phase of plasticity-related gene regulation and SRF dependent transcription in the hippocampusCorrelation between orphan nuclear receptor Nurr1 expression and amyloid deposition in 5XFAD mice, an animal model of Alzheimer's disease.Gene expression changes in serotonin, GABA-A receptors, neuropeptides and ion channels in the dorsal raphe nucleus of adolescent alcohol-preferring (P) rats following binge-like alcohol drinkingNURR1 in Parkinson disease--from pathogenesis to therapeutic potential.Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repairCombined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease.Silver nanoparticles induce tight junction disruption and astrocyte neurotoxicity in a rat blood-brain barrier primary triple coculture modelProstanoid EP₁ receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB.Prostaglandins from Cytosolic Phospholipase A2α/Cyclooxygenase-1 Pathway and Mitogen-activated Protein Kinases Regulate Gene Expression in Candida albicans-infected Macrophages.Crosstalk between phosphodiesterase 7 and glycogen synthase kinase-3: two relevant therapeutic targets for neurological disorders.In vitro generation of mature midbrain-type dopamine neurons by adjusting exogenous Nurr1 and Foxa2 expressions to their physiologic patterns.Biological pathways to adaptability--interactions between genome, epigenome, nervous system and environment for adaptive behavior.Dissecting the role of Engrailed in adult dopaminergic neurons--Insights into Parkinson disease pathogenesisDoes PGC1α/FNDC5/BDNF Elicit the Beneficial Effects of Exercise on Neurodegenerative Disorders?Arsenic-Induced Activation of the Homeodomain-Interacting Protein Kinase 2 (HIPK2) to cAMP-Response Element Binding Protein (CREB) Axis.Oxidative stress-induced CREB upregulation promotes DNA damage repair prior to neuronal cell death protection.Nuclear receptor 4A (NR4A) family - orphans no more.The NR4A subfamily of nuclear receptors: potential new therapeutic targets for the treatment of inflammatory diseases.Activation of Nur77 in microglia attenuates proinflammatory mediators production and protects dopaminergic neurons from inflammation-induced cell death.The new iminothiadiazole derivative VP1.14 ameliorates hippocampal damage after an excitotoxic injury.Huntington's Disease and Mitochondria.The Transcription Factor NURR1 Exerts Concentration-Dependent Effects on Target Genes Mediating Distinct Biological Processes.Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease.Relevance of the NR4A sub-family of nuclear orphan receptors in trophoblastic BeWo cell differentiation.Therapeutic utility of phosphodiesterase type I inhibitors in neurological conditions.Role of nuclear receptor NR4A2 in gastrointestinal inflammation and cancers.Nurr1 and PPARγ protect PC12 cells against MPP(+) toxicity: involvement of selective genes, anti-inflammatory, ROS generation, and antimitochondrial impairment.Steroid and Xenobiotic Receptor Signalling in Apoptosis and Autophagy of the Nervous System.
P2860
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P2860
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
description
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2010
@ast
im Juli 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/07/06)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/07/06)
@nl
наукова стаття, опублікована в липні 2010
@uk
name
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@ast
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@en
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@nl
type
label
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@ast
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@en
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@nl
prefLabel
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@ast
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@en
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@nl
P2093
P2860
P921
P356
P1476
NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection
@en
P2093
Banafsheh Kadkhodaei
Eliza Joodmardi
Jessica Silvaggi
Karin Wallis
Lia Panman
Nikolaos Volakakis
Thomas Perlmann
P2860
P304
12317–12322
P356
10.1073/PNAS.1007088107
P407
P577
2010-07-06T00:00:00Z