Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease
about
Genes associated with Alzheimer's disease: an overview and current statusThe amyloid hypothesis of Alzheimer's disease at 25 yearsThe roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer diseaseGenetics ignite focus on microglial inflammation in Alzheimer's diseaseLate-Onset Alzheimer's Disease Genes and the Potentially Implicated PathwaysThe dendritic hypothesis for Alzheimer's disease pathophysiology.Do Microglia Default on Network Maintenance in Alzheimer's Disease?ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.Rare-variant extensions of the transmission disequilibrium test: application to autism exome sequence data.Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.Possible modification of Alzheimer's disease by statins in midlife: interactions with genetic and non-genetic risk factorsFunctional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology.Amyloid-beta and Alzheimer's disease: the role of neprilysin-2 in amyloid-beta clearanceIdentification and characterization of Aβ peptide interactors in Alzheimer's disease by structural approaches.Alzheimer's and ABC transporters--new opportunities for diagnostics and treatment.Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearanceAlzheimer's disease risk genes and mechanisms of disease pathogenesisAlterations in function and expression of ABC transporters at blood-brain barrier under diabetes and the clinical significances.Elevation in sphingomyelin synthase activity is associated with increases in amyloid-beta peptide generation.Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary.Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.Rare coding mutations identified by sequencing of Alzheimer disease genome-wide association studies loci.ATP-binding cassette transporter A7 (ABCA7) loss of function alters Alzheimer amyloid processing.Anti-Aβ antibodies incapable of reducing cerebral Aβ oligomers fail to attenuate spatial reference memory deficits in J20 mice.Microglial malfunction: the third rail in the development of Alzheimer's disease.Abca7 deletion does not affect adult neurogenesis in the mouse.ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology.ABCA7 rare variants and Alzheimer disease riskABCA7 expression is associated with Alzheimer's disease polymorphism and disease statusThe neuropathology of obesity: insights from human disease.ABCA7 in Alzheimer's Disease.Alzheimer's disease genetics: from the bench to the clinic.Alzheimer's Disease Risk Genes and Lipid Regulators.Sex Hormone Decline and Amyloid β Synthesis, Transport and Clearance in the Brain.Study on Lentivirus-Mediated ABCA7 Improves Neurocognitive Function and Related Mechanisms in the C57BL/6 Mouse Model of Alzheimer's Disease.From Common to Rare Variants: The Genetic Component of Alzheimer Disease.Clearance of cerebral Aβ in Alzheimer's disease: reassessing the role of microglia and monocytes.Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology.Untangling Genetic Risk for Alzheimer's Disease.Deleterious ABCA7 mutations and transcript rescue mechanisms in early onset Alzheimer's disease.
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P2860
Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease
description
2013 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2013
@ast
im März 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/03/06)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/03/06)
@nl
наукова стаття, опублікована в березні 2013
@uk
مقالة علمية (نشرت في 6-3-2013)
@ar
name
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@ast
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@en
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@nl
type
label
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@ast
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@en
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@nl
prefLabel
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@ast
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@en
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@nl
P2093
P3181
P1476
Deletion of Abca7 increases ce ...... e model of Alzheimer's disease
@en
P2093
Brett Garner
David A Elliott
David Cheng
Jac Kee Low
Kalani Ruberu
Sharon Chan
Woojin S Kim
P304
P3181
P356
10.1523/JNEUROSCI.4165-12.2013
P407
P577
2013-03-01T00:00:00Z