about
Catalytic activity of ADAM8, ADAM15, and MDC-L (ADAM28) on synthetic peptide substrates and in ectodomain cleavage of CD23FLRG, a new ADAM12-associated protein, modulates osteoclast differentiationADAM8 expression is associated with increased invasiveness and reduced patient survival in pancreatic cancerADAM-8, a metalloproteinase, drives acute allergen-induced airway inflammationBidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesisThe metalloprotease disintegrin ADAM8. Processing by autocatalysis is required for proteolytic activity and cell adhesionThe metalloprotease-disintegrin ADAM8 is essential for the development of experimental asthmaADAM8 enhances osteoclast precursor fusion and osteoclast formation in vitro and in vivoADAM8: a new therapeutic target for asthmaAlpha9beta1: a novel osteoclast integrin that regulates osteoclast formation and functionRegulation of osteoclast differentiationCloning and characterization of the annexin II receptor on human marrow stromal cells.Complex dynamics of osteoclast formation and death in long-term cultures.Human parainfluenza virus type 2 (HPIV2) induced host ADAM8 expression in human salivary adenocarcinoma cell line (HSY) during cell fusion.ADAM12 and alpha9beta1 integrin are instrumental in human myogenic cell differentiation.ADAMTS and ADAM metalloproteinases in osteoarthritis - looking beyond the 'usual suspects'.Recent advances in understanding the mechanisms of osteoclast precursor fusion.The glycoprotein B disintegrin-like domain binds beta 1 integrin to mediate cytomegalovirus entry.N-glycosylation regulates ADAM8 processing and activationAtp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption.RNA therapeutics targeting osteoclast-mediated excessive bone resorption.Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis.The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts.Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling.Osteoclast fusion and regulation by RANKL-dependent and independent factors.Implication of ADAM-8, -9, -10, -12, -15, -17, and ADAMTS-1 in implantational remodeling of a mouse uterus.Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: a longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice.ADAM8 in asthma. Friend or foe to airway inflammation?Bone metastases in lung cancer. Potential novel approaches to therapy.Protective effects of ADAM8 against cisplatin-mediated apoptosis in non-small-cell lung cancer.Novel alternatively spliced ADAM8 isoforms contribute to the aggressive bone metastatic phenotype of lung cancer.ADAM8 is a negative regulator of retinal neovascularization and of the growth of heterotopically injected tumor cells in mice.Regulated proteolysis of nonmuscle myosin IIA stimulates osteoclast fusion.Differential activation of NF-kappaB and gene expression in oral epithelial cells by periodontal pathogens.An assessment of ADAMs in bone cells: absence of TACE activity prevents osteoclast recruitment and the formation of the marrow cavity in developing long bones.Inhibition of matrix metalloproteinase-9 activity by doxycycline ameliorates RANK ligand-induced osteoclast differentiation in vitro and in vivo.Comparative analysis of gingival crevicular fluid a disintegrin and metalloproteinase 8 levels in health and periodontal disease: A clinic-biochemical study.Reduced incidence and severity of experimental autoimmune arthritis in mice expressing catalytically inactive A disintegrin and metalloproteinase 8 (ADAM8).Possible early prediction of preterm birth by determination of novel proinflammatory factors in midtrimester amniotic fluid.Elevated levels of a disintegrin and metalloproteinase 8 in gingival crevicular fluid of patients with periodontal diseases.
P2860
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P2860
description
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Mai 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/05/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/05/01)
@nl
наукова стаття, опублікована в травні 2001
@uk
مقالة علمية (نشرت في مايو 2001)
@ar
name
ADAM8: a novel osteoclast stimulating factor
@ast
ADAM8: a novel osteoclast stimulating factor
@en
ADAM8: a novel osteoclast stimulating factor
@nl
type
label
ADAM8: a novel osteoclast stimulating factor
@ast
ADAM8: a novel osteoclast stimulating factor
@en
ADAM8: a novel osteoclast stimulating factor
@nl
prefLabel
ADAM8: a novel osteoclast stimulating factor
@ast
ADAM8: a novel osteoclast stimulating factor
@en
ADAM8: a novel osteoclast stimulating factor
@nl
P2093
P1476
ADAM8: a novel osteoclast stimulating factor
@en
P2093
G. D. Roodman
S. J. Choi
P304
P356
10.1359/JBMR.2001.16.5.814
P577
2001-05-01T00:00:00Z