Mouse RIC-3, an endoplasmic reticulum chaperone, promotes assembly of the alpha7 acetylcholine receptor through a cytoplasmic coiled-coil domain
about
Macoilin, a conserved nervous system-specific ER membrane protein that regulates neuronal excitabilityβ-Subunit of the Ostα-Ostβ organic solute transporter is required not only for heterodimerization and trafficking but also for functionLooking below the surface of nicotinic acetylcholine receptorsRIC-3 exclusively enhances the surface expression of human homomeric 5-hydroxytryptamine type 3A (5-HT3A) receptors despite direct interactions with 5-HT3A, -C, -D, and -E subunitsRic-3 promotes alpha7 nicotinic receptor assembly and trafficking through the ER subcompartment of dendrites.The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7.Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.Cell-specific effects on surface α7 nicotinic receptor expression revealed by over-expression and knockdown of rat RIC3 protein.Lynx1 shifts α4β2 nicotinic receptor subunit stoichiometry by affecting assembly in the endoplasmic reticulum.RIC-3 differentially modulates α4β2 and α7 nicotinic receptor assembly, expression, and nicotine-induced receptor upregulationFunctional Chimeras of GLIC Obtained by Adding the Intracellular Domain of Anion- and Cation-Conducting Cys-Loop Receptors.Resistance to Inhibitors of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations with the Human α7-Nicotinic Acetylcholine Receptor Interactome.RIC-3 expression and splicing regulate nAChR functional expression.Mechanosensitivity of nicotinic receptorsHippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder.
P2860
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P2860
Mouse RIC-3, an endoplasmic reticulum chaperone, promotes assembly of the alpha7 acetylcholine receptor through a cytoplasmic coiled-coil domain
description
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Oktober 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/10/07)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/10/07)
@nl
наукова стаття, опублікована в жовтні 2009
@uk
مقالة علمية (نشرت في 7-10-2009)
@ar
name
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@ast
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@en
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@nl
type
label
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@ast
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@en
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@nl
prefLabel
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@ast
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@en
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@nl
P2093
P2860
P921
P3181
P1476
Mouse RIC-3, an endoplasmic re ...... cytoplasmic coiled-coil domain
@en
P2093
Xiao-Qing Tang
Zuo-Zhong Wang
P2860
P304
12625–12635
P3181
P356
10.1523/JNEUROSCI.1776-09.2009
P407
P577
2009-10-07T00:00:00Z