The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency
about
Etiology and early pathogenesis of malignant testicular germ cell tumors: towards possibilities for preinvasive diagnosisChromatin dynamics during cellular reprogrammingZebrafish Germ Cell TumorsReprogramming of germ cells into pluripotencyInteraction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ lineGenome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testisFetal cyclophosphamide exposure induces testicular cancer and reduced spermatogenesis and ovarian follicle numbers in miceSignaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell developmentDMRT1 prevents female reprogramming in the postnatal mammalian testisThe mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cellsDMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovaryA second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibilityVariants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancerThe genomic landscape of testicular germ cell tumours: from susceptibility to treatment.Genome editing reveals dmrt1 as an essential male sex-determining gene in Chinese tongue sole (Cynoglossus semilaevis)Seminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell linesTumor loci and their interactions on mouse chromosome 19 that contribute to testicular germ cell tumorsDevelopment of retroviral vectors for tissue-restricted expression in chicken embryonic gonadsCharacterization of Lgr5+ Progenitor Cell Transcriptomes after Neomycin Injury in the Neonatal Mouse CochleaDissecting the molecular pathways of (testicular) germ cell tumour pathogenesis; from initiation to treatment-resistance.ATRX has a critical and conserved role in mammalian sexual differentiationMitotic arrest in teratoma susceptible fetal male germ cellsIdentification and characterization of germ cell genes expressed in the F9 testicular teratoma stem cell lineDmrt1 mutation causes a male-to-female sex reversal after the sex determination by Dmy in the medaka.Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors.Fetal radiation exposure induces testicular cancer in genetically susceptible miceThe ter mutation in the rat Dnd1 gene initiates gonadal teratomas and infertility in both gendersGenome-wide profiling of pluripotent cells reveals a unique molecular signature of human embryonic germ cells.The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis.Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads.Pathway-based analysis of GWAs data identifies association of sex determination genes with susceptibility to testicular germ cell tumors.Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background.Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility.All (C57BL/6) Mice are not Created Equal.A big catch for germ cell tumour research.Identifying disruptors of male germ cell development by small molecule screening in ex vivo gonad cultures.Transcription factor TFAP2C regulates major programs required for murine fetal germ cell maintenance and haploinsufficiency predisposes to teratomas in male miceEffects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability.DSDs: genetics, underlying pathologies and psychosexual differentiation.Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice
P2860
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P2860
The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency
description
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2009
@ast
im Dezember 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/12/29)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/12/29)
@nl
наукова стаття, опублікована в грудні 2009
@uk
name
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@ast
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@en
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@nl
type
label
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@ast
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@en
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@nl
prefLabel
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@ast
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@en
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@nl
P2093
P2860
P3181
P356
P1476
The DM domain protein DMRT1 is ...... proliferation and pluripotency
@en
P2093
Aaron L Sarver
Angabin Matin
Anthony D Krentz
Blanche Capel
David Zarkower
Keith L Parker
Mark W Murphy
Matthew S Cook
Michael D Griswold
P2860
P304
22323-22328
P3181
P356
10.1073/PNAS.0905431106
P407
P577
2009-12-10T00:00:00Z