Elucidation of the substrate binding site of Siah ubiquitin ligase
about
Alpha-synuclein biology in Lewy body diseasesStructure-Based Design of Covalent Siah InhibitorsStructure of the SCAN Domain of Human Paternally Expressed Gene 3 ProteinTwo high-resolution structures of the human E3 ubiquitin ligase Siah1Drebrin-mediated microtubule-actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selectionsiah-1 Protein is necessary for high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation and cell death in Muller cellsDirect ubiquitination of beta-catenin by Siah-1 and regulation by the exchange factor TBL1.The ubiquitin ligase Siah2 and the hypoxia response.Investigating the molecular basis of Siah1 and Siah2 E3 ubiquitin ligase substrate specificity.Inhibition of Siah ubiquitin ligase function.Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exitFunctional role of KLF10 in multiple disease processesHerpes simplex virus immediate-early protein ICP0 is targeted by SIAH-1 for proteasomal degradation.The ubiquitin ligase Siah is a novel regulator of Zeb1 in breast cancer.Identification of a Src tyrosine kinase/SIAH2 E3 ubiquitin ligase pathway that regulates C/EBPδ expression and contributes to transformation of breast tumor cells.The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer.The ubiquitin ligase Siah2 regulates tumorigenesis and metastasis by HIF-dependent and -independent pathways.Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry?Effect of disrupting seven-in-absentia homolog 2 function on lung cancer cell growthThe Siah2-HIF-FoxA2 axis in prostate cancer – new markers and therapeutic opportunities.α-Synuclein posttranslational modification and alternative splicing as a trigger for neurodegeneration.Nuclear GAPDH: changing the fate of Müller cells in diabetes.Phylogenetic analysis of the SINA/SIAH ubiquitin E3 ligase family in Metazoa.The SIAH E3 ubiquitin ligases promote Wnt/β-catenin signaling through mediating Wnt-induced Axin degradation.Bag-1 promotes cell survival through c-Myc-mediated ODC upregulation that is not preferred under apoptotic stimuli in MCF-7 cells.SIAH ubiquitin ligases target the nonreceptor tyrosine kinase ACK1 for ubiquitinylation and proteasomal degradation.Mutual regulation between SIAH2 and DYRK2 controls hypoxic and genotoxic signaling pathways.Identification of novel dioxin-responsive genes by representational difference analysis.TIN2 stability is regulated by the E3 ligase Siah2.Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases.Seven in Absentia E3 Ubiquitin Ligases: Central Regulators of Neural Cell Fate and Neuronal Polarity.The E3 ubiquitin ligase Siah-1 suppresses avian reovirus infection by targeting p10 for degradation.Polo-like kinase 3, hypoxic responses, and tumorigenesis.Mutual regulation between Polo-like kinase 3 and SIAH2 E3 ubiquitin ligase defines a regulatory network that fine-tunes the cellular response to hypoxia and nickel.Inhibition of Siah2 Ubiquitin Ligase by Vitamin K3 Attenuates Chronic Myeloid Leukemia Chemo-Resistance in Hypoxic Microenvironment.A New Strategy to Control and Eradicate "Undruggable" Oncogenic K-RAS-Driven Pancreatic Cancer: Molecular Insights and Core Principles Learned from Developmental and Evolutionary BiologyInteraction between the cellular E3 ubiquitin ligase SIAH-1 and the viral immediate-early protein ICP0 enables efficient replication of Herpes Simplex Virus type 2 in vivo
P2860
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P2860
Elucidation of the substrate binding site of Siah ubiquitin ligase
description
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im April 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2006/04/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/04/01)
@nl
наукова стаття, опублікована у квітні 2006
@uk
مقالة علمية (نشرت في أبريل 2006)
@ar
name
Elucidation of the substrate binding site of Siah ubiquitin ligase
@ast
Elucidation of the substrate binding site of Siah ubiquitin ligase
@en
Elucidation of the substrate binding site of Siah ubiquitin ligase
@nl
type
label
Elucidation of the substrate binding site of Siah ubiquitin ligase
@ast
Elucidation of the substrate binding site of Siah ubiquitin ligase
@en
Elucidation of the substrate binding site of Siah ubiquitin ligase
@nl
prefLabel
Elucidation of the substrate binding site of Siah ubiquitin ligase
@ast
Elucidation of the substrate binding site of Siah ubiquitin ligase
@en
Elucidation of the substrate binding site of Siah ubiquitin ligase
@nl
P2093
P50
P1433
P1476
Elucidation of the substrate binding site of Siah ubiquitin ligase
@en
P2093
Andreas Möller
Colin M House
Galina Polekhina
Nancy C Hancock
Victor Fedorov
P304
P356
10.1016/J.STR.2005.12.013
P577
2006-04-01T00:00:00Z