Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
about
Telomere dysfunction and chromosome instabilityDNA damage signalling prevents deleterious telomere addition at DNA breaksBLM helicase facilitates telomere replication during leading strand synthesis of telomeresThe TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasisInactivation of Pif1 helicase causes a mitochondrial myopathy in miceUnwinding the functions of the Pif1 family helicases.A genomewide screen for suppressors of Alu-mediated rearrangements reveals a role for PIF1Telomeres: structures in need of unwinding.Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.The Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening.PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells.The Insertion in Fingers Domain in Human Telomerase Can Mediate Enzyme Processivity and Telomerase Recruitment to Telomeres in a TPP1-Dependent Manner.Multiple Mechanisms Contribute to the Cell Growth Defects Imparted by Human Telomerase Insertion in Fingers Domain Mutations Associated with Premature Aging Diseases.Mechanisms of telomere loss and their consequences for chromosome instability.DNA repair at telomeres: keeping the ends intact.Telomeres do the (un)twist: helicase actions at chromosome termini.The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivoTelomerase is essential to alleviate pif1-induced replication stress at telomeres.Non-telomeric activities of telomerase.Telomerase regulation.Regulation of telomere addition at DNA double-strand breaks.To peep into Pif1 helicase: multifaceted all the way from genome stability to repair-associated DNA synthesis.Mitochondrial DNA maintenance: an appraisal.Non-B DNA Secondary Structures and Their Resolution by RecQ Helicases.Getting it done at the ends: Pif1 family DNA helicases and telomeres.Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress.Solving the Telomere Replication Problem.De novo telomere formation is suppressed by the Mec1-dependent inhibition of Cdc13 accumulation at DNA breaks.The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability.Human Pif1 helicase unwinds synthetic DNA structures resembling stalled DNA replication forks.Pif1-family helicases cooperatively suppress widespread replication-fork arrest at tRNA genes.The Schizosaccharomyces pombe Pfh1p DNA helicase is essential for the maintenance of nuclear and mitochondrial DNA.Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity
P2860
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P2860
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
description
2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Februar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/02/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/02/01)
@nl
наукова стаття, опублікована в лютому 2007
@uk
مقالة علمية (نشرت في فبراير 2007)
@ar
name
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@ast
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@en
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@nl
type
label
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@ast
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@en
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@nl
prefLabel
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@ast
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@en
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@nl
P2093
P2860
P356
P1476
Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo
@en
P2093
Andrew Wakeham
Bryan E. Snow
Caterina Iorio
Jana Paderova
Lea Harrington
Virginia Zakian
P2860
P304
P356
10.1128/MCB.01866-06
P407
P577
2007-02-01T00:00:00Z