Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress
about
The relationship between the MMP system, adrenoceptors and phosphoprotein phosphatasesThe Multifaceted Roles of PI3Kγ in Hypertension, Vascular Biology, and InflammationSaturated palmitic acid induces myocardial inflammatory injuries through direct binding to TLR4 accessory protein MD2Anthocyanins protected hearts against ischemic injury by reducing MMP-2 activity via Akt/P38 pathwaysTRPV2 is critical for the maintenance of cardiac structure and function in mice.Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit.Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunctionAntagonism of angiotensin 1-7 prevents the therapeutic effects of recombinant human ACE2New Cell Adhesion Molecules in Human Ischemic Cardiomyopathy. PCDHGA3 Implications in Decreased Stroke Volume and Ventricular Dysfunction.AKT2 confers protection against aortic aneurysms and dissections.Loss of angiotensin-converting enzyme-2 exacerbates diabetic cardiovascular complications and leads to systolic and vascular dysfunction: a critical role of the angiotensin II/AT1 receptor axisTestosterone delays vascular smooth muscle cell senescence and inhibits collagen synthesis via the Gas6/Axl signaling pathway.Loss of Apelin exacerbates myocardial infarction adverse remodeling and ischemia-reperfusion injury: therapeutic potential of synthetic Apelin analogues.Specific PI3K isoform modulation in heart failure: lessons from transgenic mice.Endogenous migration modulators as parent compounds for the development of novel cardiovascular and anti-inflammatory drugs.An emerging role of degrading proteinases in hypertension and the metabolic syndrome: autodigestion and receptor cleavage.Regulation of myocardial matrix metalloproteinase expression and activity by cardiac fibroblasts.A pathway and network review on beta-adrenoceptor signaling and beta blockers in cardiac remodeling.Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction.β-adrenergic receptor stimulation transactivates protease-activated receptor 1 via matrix metalloproteinase 13 in cardiac cells.Phosphoinositide 3-kinase γ affects LPS-induced disturbance of blood-brain barrier via lipid kinase-independent control of cAMP in microglial cells.miR-139-5p inhibits isoproterenol-induced cardiac hypertrophy by targeting c-Jun.Heterozygote loss of ACE2 is sufficient to increase the susceptibility to heart disease.Increased proliferation and adhesion properties of human dental pulp stem cells in PLGA scaffolds via simulated microgravity.Sgk1 sensitivity of Na(+)/H(+) exchanger activity and cardiac remodeling following pressure overload.
P2860
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P2860
Loss of PI3Kγ enhances cAMP-dependent MMP remodeling of the myocardial N-cadherin adhesion complexes and extracellular matrix in response to early biomechanical stress
description
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im November 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/11/12)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/11/12)
@nl
наукова стаття, опублікована в листопаді 2010
@uk
مقالة علمية (نشرت في 12-11-2010)
@ar
name
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@ast
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@en
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@nl
type
label
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@ast
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@en
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@nl
prefLabel
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@ast
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@en
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@nl
P2093
P3181
P1433
P1476
Loss of PI3Kγ enhances cAMP-de ...... to early biomechanical stress
@en
P2093
Federico Damilano
Fung L. Chow
Gavin Y. Oudit
Josef M. Penninger
Peter H. Backx
Ratnadeep Basu
Seigo Izumo
Vijay Kandalam
Wenbin Liang
P304
P3181
P356
10.1161/CIRCRESAHA.110.229054
P577
2010-11-12T00:00:00Z