Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene
about
Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancerDistinct roles for mitogen-activated protein kinase phosphatase-1 (MKP-1) and ERK-MAPK in PTH1R signaling during osteoblast proliferation and differentiationBcl-2 lies downstream of parathyroid hormone-related peptide in a signaling pathway that regulates chondrocyte maturation during skeletal developmentStructural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptidesMendelian forms of human hypertension and mechanisms of diseaseParathyroid hormone is essential for normal fetal bone formationAbsence of functional receptors for parathyroid hormone and parathyroid hormone-related peptide in Blomstrand chondrodysplasiaIndian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formationMammary-specific deletion of parathyroid hormone-related protein preserves bone mass during lactationPref-1 regulates mesenchymal cell commitment and differentiation through Sox9Parathyroid hormone receptor type 1/Indian hedgehog expression is preserved in the growth plate of human fetuses affected with fibroblast growth factor receptor type 3 activating mutationsParathyroid hormone-related protein is required for tooth eruptionThe association between environmental lead exposure and bone density in childrenA pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationDimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced DissociationReceptors for PTH and PTHrP: their biological importance and functional propertiesRor2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate developmentThe COOH-terminus of parathyroid hormone-related protein (PTHrP) interacts with beta-arrestin 1BSixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasiasAdvances in Skeletal Dysplasia GeneticsHomozygous ablation of fibroblast growth factor-23 results in hyperphosphatemia and impaired skeletogenesis, and reverses hypophosphatemia in Phex-deficient miceDeficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical boneThe chondrogenic transcription factor Sox9 is a target of signaling by the parathyroid hormone-related peptide in the growth plate of endochondral bonesCooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilageMechanical regulation of terminal chondrocyte differentiation via RGD-CAP/beta ig-h3 induced by TGF-betaCoordination of chondrogenesis and osteogenesis by fibroblast growth factor 18Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilageCystatin 10, a novel chondrocyte-specific protein, may promote the last steps of the chondrocyte differentiation pathwayTargeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalitiesIndian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrPThe transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6The Unicellular State as a Point Source in a Quantum Biological SystemMolecular development of fibular reduction in birds and its evolution from dinosaursOn the evolution of developmentEvolution and Cell Physiology. 1. Cell signaling is all of biologyThe transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossificationTwenty-five years of PTHrP progress: from cancer hormone to multifunctional cytokine.Inhibition of ALK5 signaling induces physeal dysplasia in rats.The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturationDeletion of the nuclear localization sequences and C-terminus of PTHrP impairs embryonic mammary development but also inhibits PTHrP production.
P2860
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P2860
Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene
description
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im Februar 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/02/01)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/02/01)
@nl
наукова стаття, опублікована в лютому 1994
@uk
مقالة علمية (نشرت في فبراير 1994)
@ar
name
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@ast
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@en
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@nl
type
label
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@ast
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@en
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@nl
prefLabel
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@ast
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@en
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@nl
P2093
P3181
P356
P1433
P1476
Lethal skeletal dysplasia from ...... d hormone-related peptide gene
@en
P2093
A. C. Karaplis
H. M. Kronenberg
J. Glowacki
R. C. Mulligan
R. T. Bronson
V. L. Tybulewicz
P304
P3181
P356
10.1101/GAD.8.3.277
P577
1994-02-01T00:00:00Z