Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span
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MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine responseThe isolation and characterization of a cDNA encoding phospholipid-specific inositol polyphosphate 5-phosphatasep56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transductionIdentification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...The molecular mechanisms that control thrombopoiesisNck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activationInositol phosphatase SHIP1 is a primary target of miR-155Phosphoinositide 3-kinase: a critical signalling event in pulmonary cellsRegulation of osteoclasts by membrane-derived lipid mediatorsInositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathiesPhosphoinositides: tiny lipids with giant impact on cell regulationMurine xenogeneic models of myelodysplastic syndrome: an essential role for stroma cellsThe prognostic and functional role of microRNAs in acute myeloid leukemiap135 src homology 2 domain-containing inositol 5'-phosphatase (SHIPbeta ) isoform can substitute for p145 SHIP in fcgamma RIIB1-mediated inhibitory signaling in B cellsThe SH2 inositol 5-phosphatase Ship1 is recruited in an SH2-dependent manner to the erythropoietin receptorThe Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cellsThe inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activitySignaling via Shc family adapter proteinsRegulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene productHematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell CistromeMammalian inositol polyphosphate 5-phosphatase II can compensate for the absence of all three yeast Sac1-like-domain-containing 5-phosphatasesCloning and characterization of a 72-kDa inositol-polyphosphate 5-phosphatase localized to the Golgi networkThe inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.Inpp5f is a polyphosphoinositide phosphatase that regulates cardiac hypertrophic responsivenessA dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- miceSHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKLInositol polyphosphate 4-phosphatase type I regulates cell growth downstream of transcription factor GATA-1Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespanSHIP-deficient dendritic cells, unlike wild type dendritic cells, suppress T cell proliferation via a nitric oxide-independent mechanismA small-molecule inhibitor of SHIP1 reverses age- and diet-associated obesity and metabolic syndromeSHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase.Essential role for the C-terminal noncatalytic region of SHIP in FcgammaRIIB1-mediated inhibitory signalingA key role for the phosphorylation of Ser440 by the cyclic AMP-dependent protein kinase in regulating the activity of the Src homology 2 domain-containing Inositol 5'-phosphatase (SHIP1).Caenorhabditis elegans inositol 5-phosphatase homolog negatively regulates inositol 1,4,5-triphosphate signaling in ovulation.A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.Tumor suppressor PTEN is a physiologic suppressor of chemoattractant-mediated neutrophil functionsOral infection of mice with Salmonella enterica serovar Typhimurium causes meningitis and infection of the brainSHIP-1 increases early oxidative burst and regulates phagosome maturation in macrophages.The SH2-domain-containing inositol 5-phosphatase (SHIP) limits the motility of neutrophils and their recruitment to wounds in zebrafishThe inositol polyphosphate 5-phosphatases and the apurinic/apyrimidinic base excision repair endonucleases share a common mechanism for catalysis.
P2860
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P2860
Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span
description
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1998
@ast
im Juni 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/06/01)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/06/01)
@nl
наукова стаття, опублікована в червні 1998
@uk
مقالة علمية (نشرت في يونيو 1998)
@ar
name
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@ast
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@en
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@nl
type
label
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@ast
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@en
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@nl
prefLabel
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@ast
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@en
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@nl
P2093
P2860
P3181
P356
P1433
P1476
Targeted disruption of SHIP le ...... ogy, and a shortened life span
@en
P2093
A. Borowski
C. D. Helgason
G. Krystal
J. E. Damen
P. Sorensen
R. K. Humphries
S. M. Chappel
P2860
P304
P3181
P356
10.1101/GAD.12.11.1610
P577
1998-06-01T00:00:00Z