Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss.
about
Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activationTmprss3, a transmembrane serine protease deficient in human DFNB8/10 deafness, is critical for cochlear hair cell survival at the onset of hearing.Thyroxine treatments do not correct inner ear defects in tmprss1 mutant mice.Pla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterolAge-related changes of myelin basic protein in mouse and human auditory nerve.Unmyelinated auditory type I spiral ganglion neurons in congenic Ly5.1 mice.Membrane-anchored serine proteases in vertebrate cell and developmental biologyExpression and genetic loss of function analysis of the HAT/DESC cluster proteases TMPRSS11A and HATFunctional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea.Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Membrane-anchored serine proteases in health and disease.Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse model.Nardilysin convertase regulates the function of the maxi-K channel isoform mK44 in human myometriumType II transmembrane serine proteases as potential targets for cancer therapy.Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasisTMPRSS4 correlates with colorectal cancer pathological stage and regulates cell proliferation and self-renewal ability.The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss.The role of type II transmembrane serine protease-mediated signaling in cancer.Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms.Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice.Macrophage-Mediated Glial Cell Elimination in the Postnatal Mouse Cochlea.
P2860
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P2860
Mice deficient for the type II transmembrane serine protease, TMPRSS1/hepsin, exhibit profound hearing loss.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Mice deficient for the type II ...... exhibit profound hearing loss
@nl
Mice deficient for the type II ...... exhibit profound hearing loss.
@ast
Mice deficient for the type II ...... exhibit profound hearing loss.
@en
type
label
Mice deficient for the type II ...... exhibit profound hearing loss
@nl
Mice deficient for the type II ...... exhibit profound hearing loss.
@ast
Mice deficient for the type II ...... exhibit profound hearing loss.
@en
prefLabel
Mice deficient for the type II ...... exhibit profound hearing loss
@nl
Mice deficient for the type II ...... exhibit profound hearing loss.
@ast
Mice deficient for the type II ...... exhibit profound hearing loss.
@en
P2093
P2860
P1476
Mice deficient for the type II ...... exhibit profound hearing loss.
@en
P2093
Justin Tan
Lauren Donley
Maria Clarke
Michel Guipponi
Pauline Crewther
Ping Z F Cannon
P2860
P304
P356
10.2353/AJPATH.2007.070068
P407
P577
2007-07-09T00:00:00Z