Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V
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Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factorThe plasminogen activator inhibitor-2 gene is not required for normal murine development or survivalInactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in miceA targeted point mutation in thrombomodulin generates viable mice with a prethrombotic stateLaser-induced noninvasive vascular injury models in mice generate platelet- and coagulation-dependent thrombiDefective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans.Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice.Alternatively spliced tissue factor is not sufficient for embryonic developmentHow the protease thrombin talks to cells.Comparative response of platelet fV and plasma fV to activated protein C and relevance to a model of acute traumatic coagulopathy.Hemostasis and alterations of the central nervous systemFactor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit.Special considerations in the evaluation of the hematology and hemostasis of mutant mice.Identification of the MMRN1 binding region within the C2 domain of human factor V.Blood coagulation factors V and VIII: Molecular Mechanisms of Procofactor Activation.Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domainAutosomal recessive deficiencies of coagulation factors.Rare coagulation deficiencies.Genetic sequence analysis of inherited bleeding diseases.The Fgl2/fibroleukin prothrombinase contributes to immunologically mediated thrombosis in experimental and human viral hepatitisProtease-activated receptors in the cardiovascular system.Fatal hemorrhage in mice lacking gamma-glutamyl carboxylase.Blood coagulation and its regulation by anticoagulant pathways: genetic pathogenesis of bleeding and thrombotic diseases.Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.Mining copper transport genes.Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development.Effect of tissue factor deficiency on mouse and tumor development.A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280.Inherited defects of coagulation factor V: the hemorrhagic side.Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation.Prothrombin deficiency results in embryonic and neonatal lethality in mice.Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin deficiency in miceA guide to murine coagulation factor structure, function, assays, and genetic alterations.The hemostasis system in murine atherosclerosis.Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency.Genetic elimination of prothrombin in adult mice is not compatible with survival and results in spontaneous hemorrhagic events in both heart and brain.Reduced thrombin generation increases host susceptibility to group A streptococcal infectionInterpreting neonatal lethal phenotypes in mouse mutants: insights into gene function and human diseases.Does plasmin have anticoagulant activity?Historical perspective and future direction of coagulation research.
P2860
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P2860
Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V
description
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 1996
@ast
scientific journal article
@en
vedecký článok (publikovaný 1996/11/07)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/11/07)
@nl
наукова стаття, опублікована в листопаді 1996
@uk
مقالة علمية (نشرت في 7-11-1996)
@ar
name
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@ast
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@en
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@nl
type
label
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@ast
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@en
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@nl
prefLabel
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@ast
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@en
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@nl
P2093
P356
P1433
P1476
Fatal haemorrhage and incomple ...... e lacking coagulation factor V
@en
P2093
A. Purkayastha
D. Ginsburg
K. S. O'Shea
T. L. Saunders
P2888
P356
10.1038/384066A0
P407
P577
1996-11-07T00:00:00Z
P5875
P6179
1041003191