Reversible memory loss in a mouse transgenic model of Alzheimer's disease
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Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer diseaseNasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer diseasePathways towards and away from Alzheimer's diseaseSoluble oligomers of the amyloid beta-protein impair synaptic plasticity and behaviorActive and passive immunotherapy for neurodegenerative disordersValsartan lowers brain beta-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer diseasePassive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhageNovel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease.Non-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium?Alzheimer's therapeutics: translation of preclinical science to clinical drug developmentStructural Correlates of Antibodies Associated with Acute Reversal of Amyloid -related Behavioral Deficits in a Mouse Model of Alzheimer DiseaseImmune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodiesACAT1/SOAT1 as a therapeutic target for Alzheimer's diseaseFerulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic miceDisease modifying therapies for Alzheimer's disease targeting Aβ oligomers: implications for therapeutic mechanismsExtracellular and intraneuronal HMW-AbetaOs represent a molecular basis of memory loss in Alzheimer's disease model mouseAmyloid-β oligomer specificity mediated by the IgM isotype--implications for a specific protective mechanism exerted by endogenous auto-antibodiesIs glial heme oxygenase-1 suppression in neurodegenerative disorders permissive for neural repair?Phagocytic clearance in neurodegeneration.Type 2 diabetes and Alzheimer's disease: from common pathologies to potential new therapeutics.Reduced pathology and improved behavioral performance in Alzheimer's disease mice vaccinated with HSV amplicons expressing amyloid-beta and interleukin-4.Carvedilol as a potential novel agent for the treatment of Alzheimer's disease.Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA receptors in cultured hippocampal neurons.Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.Beneficial catalytic immunity to abeta peptide.Novel amyloid-beta specific scFv and VH antibody fragments from human and mouse phage display antibody librariesAntibodies targeted to the brain with image-guided focused ultrasound reduces amyloid-beta plaque load in the TgCRND8 mouse model of Alzheimer's diseaseGenetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's diseaseDiminished amyloid-beta burden in Tg2576 mice following a prophylactic oral immunization with a salmonella-based amyloid-beta derivative vaccine.An update on the amyloid hypothesis.Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathologyBlocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model.Nanoscience enables ultrasensitive detection of Alzheimer's biomarkerTg2576 cortical neurons that express human Ab are susceptible to extracellular Aβ-induced, K+ efflux dependent neurodegenerationNeuroinflammation and related neuropathologies in APPSL mice: further value of this in vivo model of Alzheimer's disease.Amyloid-beta immunotherapy for Alzheimer's diseaseAn improved method for generating consistent soluble amyloid-beta oligomer preparations for in vitro neurotoxicity studiesDrug development for Alzheimer's disease: where are we now and where are we headed?Probing the biology of Alzheimer's disease in mice.Unintended effects of cardiovascular drugs on the pathogenesis of Alzheimer's disease
P2860
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P2860
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im August 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/08/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/08/01)
@nl
наукова стаття, опублікована в серпні 2002
@uk
مقالة علمية (نشرت في أغسطس 2002)
@ar
name
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@ast
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@en
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@nl
type
label
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@ast
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@en
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@nl
prefLabel
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@ast
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@en
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@nl
P2093
P3181
P1476
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
@en
P2093
Bradley T Hyman
Brian Bacskai
Karen H Ashe
Linda A Kotilinek
Linda Younkin
Marcus Westerman
Steven Younkin
Takeshi Kawarabayashi
P304
P3181
P356
10.1523/JNEUROSCI.22-15-06331.2002
P407
P577
2002-08-01T00:00:00Z