Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
about
Linear arrays of nuclear envelope proteins harness retrograde actin flow for nuclear movement.Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffnessMammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processesLINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteinsNesprin-3 regulates endothelial cell morphology, perinuclear cytoskeletal architecture, and flow-induced polarizationTo build a synapse: signaling pathways in neuromuscular junction assemblyLinker of nucleoskeleton and cytoskeleton (LINC) complex-mediated actin-dependent nuclear positioning orients centrosomes in migrating myoblasts.Nuclear motility in glioma cells reveals a cell-line dependent role of various cytoskeletal componentsThe Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and β-CateninLINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retinaMammalian sperm head formation involves different polarization of two novel LINC complexesImpaired neurodevelopment by the low complexity domain of CPEB4 reveals a convergent pathway with neurodegeneration.In vivo monitoring of mRNA movement in Drosophila body wall muscle cells reveals the presence of myofiber domainsRegulation of nucleocytoplasmic transport in skeletal muscle.Nuclear migration events throughout developmentNuclear envelope: positioning nuclei and organizing synapsesSUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in miceMuscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organizationA mammalian KASH domain protein coupling meiotic chromosomes to the cytoskeletonLINC'ing form and function at the nuclear envelope.Organelle positioning in muscles requires cooperation between two KASH proteins and microtubules.Opposing microtubule motors drive robust nuclear dynamics in developing muscle cells.Emerin organizes actin flow for nuclear movement and centrosome orientation in migrating fibroblasts.Linker of nucleoskeleton and cytoskeleton complex proteins in cardiac structure, function, and disease.Nesprin 1 is critical for nuclear positioning and anchorageThe missing LINC: a mammalian KASH-domain protein coupling meiotic chromosomes to the cytoskeleton.Interactions between nuclei and the cytoskeleton are mediated by SUN-KASH nuclear-envelope bridges.Lamin-binding ProteinsLoss of adult skeletal muscle stem cells drives age-related neuromuscular junction degenerationRegulation of asymmetric positioning of nuclei by Wnt and Src signaling and its roles in POP-1/TCF nuclear asymmetry in Caenorhabditis elegans.Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscleActomyosin tension exerted on the nucleus through nesprin-1 connections influences endothelial cell adhesion, migration, and cyclic strain-induced reorientation.Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope.LINCing lamin B2 to neuronal migration: growing evidence for cell-specific roles of B-type lamins.N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy.LINC complexes in health and disease.KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development.Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.Nuclear envelope in nuclear positioning and cell migrationTargeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.
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P2860
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
description
2007 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Januar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/03/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/03/01)
@nl
наукова стаття, опублікована в березні 2007
@uk
مقالة علمية (نشرت في مارس 2007)
@ar
name
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@ast
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@en
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@nl
type
label
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@ast
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@en
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@nl
prefLabel
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@ast
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@en
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@nl
P2093
P3181
P356
P1433
P1476
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation
@en
P2093
Binggen Zhu
Shumin Duan
Xiujuan Yang
Yuan Zhuang
P304
P3181
P356
10.1242/DEV.02783
P407
P577
2007-01-31T00:00:00Z