Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery
about
Comparative analysis of the human and chicken prion protein copper binding regions at pH 6.5.Prion protein self-peptides modulate prion interactions and conversion.Insights into prion protein function from atomistic simulations.Redox control of prion and disease pathogenesis.Biological characteristics of Chinese hamster ovary cells transfected with bovine PrnpCopper binding in the prion proteinPrion Protein Does Not Confer Resistance to Hippocampus-Derived Zpl Cells against the Toxic Effects of Cu2+, Mn2+, Zn2+ and Co2+ Not Supporting a General Protective Role for PrP in Transition Metal Induced Toxicity.Prion (PrPres) allotypes profiling: a new perspectives from mass spectrometry.Cellular prion protein (PrP(C)) and its role in stress responses.Copper and Zinc Interactions with Cellular Prion Proteins Change Solubility of Full-Length Glycosylated Isoforms and Induce the Occurrence of Heterogeneous PhenotypesNormal cellular prion protein protects against manganese-induced oxidative stress and apoptotic cell death.Bovine spongiform encephalopathy in Japan: history and recent studies on oxidative stress in prion diseases.Copper and the prion protein: methods, structures, function, and diseaseCytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection.Functional implications of multistage copper binding to the prion protein.Helix 3 is necessary and sufficient for prion protein's anti-Bax function.Identification of the copper(II) coordinating residues in the prion protein by metal-catalyzed oxidation mass spectrometry: evidence for multiple isomers at low copper(II) loadingsMetal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach.Physiological Functions of the Cellular Prion Protein.Prions and manganese: A maddening beast.Metal attenuating therapies in neurodegenerative disease.Review of studies that have used knockout mice to assess normal function of prion protein under immunological or pathophysiological stress.Senescence suppressors: their practical importance in replicative lifespan extension in stem cells.Prion protein and aging.Expression of Heterologous PrP and Prion Propagation in RK13 Cells.MEK1 transduces the prion protein N2 fragment antioxidant effects.Role of the cellular prion protein in the neuron adaptation strategy to copper deficiency.Conditional modulation of membrane protein expression in cultured cells mediated by prion protein recognition of short phosphorothioate oligodeoxynucleotides.Helicobacter pylori upregulates prion protein expression in gastric mucosa: a possible link to prion disease.Gene Signature of Human Oral Mucosa Fibroblasts: Comparison with Dermal Fibroblasts and Induced Pluripotent Stem Cells.Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4.Absence of the cellular prion protein exacerbates and prolongs neuroinflammation in experimental autoimmune encephalomyelitis.The role of the octarepeat region in neuroprotective function of the cellular prion protein.Fragmentation and dimerization of copper-loaded prion protein by copper-catalysed oxidation.MEDNIK syndrome: a novel defect of copper metabolism treatable by zinc acetate therapy.The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4.Copper coordination in the full-length, recombinant prion proteinFragment length influences affinity for Cu2+ and Ni2+ binding to His96 or His111 of the prion protein and spectroscopic evidence for a multiple histidine binding only at low pH.Green fluorescent protein as a reporter of prion protein folding.A human prion protein peptide (PrP(59-91)) protects against copper neurotoxicity.
P2860
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P2860
Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery
description
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2003
@ast
im März 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/03/14)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/03/14)
@nl
наукова стаття, опублікована в березні 2003
@uk
name
Expression of prion protein in ...... vities but not copper delivery
@ast
Expression of prion protein in ...... vities but not copper delivery
@en
Expression of prion protein in ...... vities but not copper delivery
@nl
type
label
Expression of prion protein in ...... vities but not copper delivery
@ast
Expression of prion protein in ...... vities but not copper delivery
@en
Expression of prion protein in ...... vities but not copper delivery
@nl
prefLabel
Expression of prion protein in ...... vities but not copper delivery
@ast
Expression of prion protein in ...... vities but not copper delivery
@en
Expression of prion protein in ...... vities but not copper delivery
@nl
P2093
P2860
P3181
P356
P1476
Expression of prion protein in ...... vities but not copper delivery
@en
P2093
Alain Favier
Didier Vilette
Hubert Laude
Jacqueline Riondel
Pascale Guiraud
Sylvain Lehmann
Walid Rachidi
P2860
P304
P3181
P356
10.1074/JBC.M211830200
P407
P577
2002-12-23T00:00:00Z