Genetic analysis of the role of proteolysis in the activation of latent myostatin
about
Latent myostatin has significant activity and this activity is controlled more efficiently by WFIKKN1 than by WFIKKN2Myostatin from the heart: local and systemic actions in cardiac failure and muscle wastingStepwise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ.Identification of Deleterious Mutations in Myostatin Gene of Rohu Carp (Labeo rohita) Using Modeling and Molecular Dynamic Simulation Approaches.Knockdown of myostatin expression by RNAi enhances muscle growth in transgenic sheepMyostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity.Cytotoxic aggregation and amyloid formation by the myostatin precursor proteinMyostatin is upregulated following stress in an Erk-dependent manner and negatively regulates cardiomyocyte growth in culture and in a mouse model.Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice.The C313Y Piedmontese mutation decreases myostatin covalent dimerisation and stability.Bowman-Birk inhibitor attenuates dystrophic pathology in mdx mice.Extracellular Regulation of Myostatin: A Molecular Rheostat for Muscle Mass.A soluble activin receptor type IIB does not improve blood glucose in streptozotocin-treated miceMetalloproteinases in Drosophila to humans that are central players in developmental processes.Targeting the myostatin signaling pathway to treat muscle wasting diseasesMaltose binding protein-fusion enhances the bioactivity of truncated forms of pig myostatin propeptide produced in E. coli.Structural and Dynamic Characterization of the C313Y Mutation in Myostatin Dimeric Protein, Responsible for the "Double Muscle" Phenotype in Piedmontese Cattle.Diversity between mammalian tolloid proteinases: Oligomerisation and non-catalytic domains influence activity and specificity.Influence of WFIKKN1 on BMP1-mediated activation of latent myostatin.Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling.Enhanced muscle growth by plasmid-mediated delivery of myostatin propeptide.cDNA sequence and protein bioinformatics analyses of MSTN in African catfish (Clarias gariepinus).Formoterol treatment downregulates the myostatin system in skeletal muscle of cachectic tumour-bearing ratsInsulin resistance and muscle metabolism in chronic kidney disease.BMP1-like proteinases are essential to the structure and wound healing of skin.Seasonal variation in pectoralis muscle and heart myostatin and tolloid-like proteinases in small birds: a regulatory role for seasonal phenotypic flexibility?Inactivation of bone morphogenetic protein 1 (Bmp1) and tolloid-like 1 (Tll1) in cells expressing type I collagen leads to dental and periodontal defects in mice.Molecular characterization of latent GDF8 reveals mechanisms of activation.Increased circulating myostatin in patients with type 2 diabetes mellitus.Endoplasmic Reticulum Stress Induces Myostatin High Molecular Weight Aggregates and Impairs Mature Myostatin Secretion.Context-dependent regulation of pectoralis myostatin and lipid transporters by temperature and photoperiod in dark-eyed juncos.GWAS and eQTL analysis identifies a SNP associated with both residual feed intake and GFRA2 expression in beef cattle
P2860
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P2860
Genetic analysis of the role of proteolysis in the activation of latent myostatin
description
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique PLoS ONE
@fr
artículu científicu espublizáu en 2008
@ast
scientific journal article
@en
vedecký článok (publikovaný 2008/02/20)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/02/20)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована в лютому 2008
@uk
name
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@ast
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@en
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@nl
type
label
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@ast
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@en
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@nl
prefLabel
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@ast
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@en
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@nl
P2860
P921
P1433
P1476
Genetic analysis of the role of proteolysis in the activation of latent myostatin
@en
P2093
Se-Jin Lee
P2860
P356
10.1371/JOURNAL.PONE.0001628
P407
P577
2008-02-20T00:00:00Z