Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration
about
Dietary and genetic manipulations of folate metabolism differentially affect neocortical functions in mice.Correlations of MTHFR 677C>T polymorphism with cardiovascular disease in patients with end-stage renal disease: a meta-analysis.Nuclear enrichment of folate cofactors and methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) protect de novo thymidylate biosynthesis during folate deficiencyHuman mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis.Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohortHigh-throughput and simultaneous quantitative analysis of homocysteine-methionine cycle metabolites and co-factors in blood plasma and cerebrospinal fluid by isotope dilution LC-MS/MS.Arsenic trioxide targets MTHFD1 and SUMO-dependent nuclear de novo thymidylate biosynthesis.MTHFD1 regulates nuclear de novo thymidylate biosynthesis and genome stability.High-throughput method for the quantitation of metabolites and co-factors from homocysteine-methionine cycle for nutritional status assessment.Paternal transmission of MTHFD1 G1958A variant predisposes to neural tube defects in the offspring.
P2860
Q30827614-4E3CD8A1-F303-4555-BF0A-C54A107E8747Q33933333-3E836AC5-4754-43A5-A143-80BC05D7CB38Q34396785-E45F1B65-C8B2-40EA-9EC3-A6CC9B33E410Q34985462-793A28C9-CF86-4B7E-AF2C-5553EFD8DC2BQ35879023-51F9AF05-C07B-473A-B55E-809560013AECQ40449503-25E98698-6C56-4037-A7BC-B80320053941Q41710207-507D15F7-AC97-4AC8-BC30-7FA2483897A1Q41808283-1643A601-DABB-44F2-86E4-D71969978D7DQ50230198-08721B96-A70D-43B9-A67C-ECFCCEE99481Q50980897-A17DE502-4C70-4C5F-B61E-3EE56556C1F8
P2860
Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration
description
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2013
@ast
im Januar 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/01/01)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/01/01)
@nl
наукова стаття, опублікована в січні 2013
@uk
مقالة علمية (نشرت عام 2013)
@ar
name
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@ast
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@en
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@nl
type
label
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@ast
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@en
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@nl
prefLabel
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@ast
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@en
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@nl
P2093
P2860
P356
P1433
P1476
Reduced MTHFD1 activity in mal ...... sm as well as transsulfuration
@en
P2093
Barbara J Strupp
Elena V Abarinov
Jessica A Ash
Kelsey S Shields
Marie A Caudill
Olga V Malysheva
Patrick J Stover
Robert H Allen
Sally P Stabler
P2860
P356
10.3945/JN.112.169821
P407
P577
2012-11-28T00:00:00Z