PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver
about
Mechanisms for insulin resistance: common threads and missing linksPERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice.Acute ablation of PERK results in ER dysfunctions followed by reduced insulin secretion and cell proliferation.Hyperthermia induces the ER stress pathway.PERK (EIF2AK3) regulates proinsulin trafficking and quality control in the secretory pathway.Wolcott-Rallison syndromeHuman stanniocalcin-2 exhibits potent growth-suppressive properties in transgenic mice independently of growth hormone and IGFs.Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease.Perk gene dosage regulates glucose homeostasis by modulating pancreatic β-cell functions.The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress.PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility.PERK is required in the adult pancreas and is essential for maintenance of glucose homeostasis.The hormonal action of IGF1 in postnatal mouse growth.Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase, PERKGenetic inactivation of PERK signaling in mouse oligodendrocytes: normal developmental myelination with increased susceptibility to inflammatory demyelination.Involvement of p38 MAPK in regulation of MMP13 mRNA in chondrocytes in response to surviving stress to endoplasmic reticulumFatty acid-mediated endoplasmic reticulum stress in vivo: differential response to the infusion of Soybean and Lard Oil in rats.PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis.Targeted intestinal overexpression of the immediate early gene tis7 in transgenic mice increases triglyceride absorption and adiposity.Human stanniocalcin-1 or -2 expressed in mice reduces bone size and severely inhibits cranial intramembranous bone growth.Equine endometrial gene expression changes during and after maternal recognition of pregnancy.Age-dependent onset of liver-specific IGF-I gene deficiency and its persistence in old age: implications for postnatal growth and insulin resistance in LID mice.Microscopic and ultrastructural features in Wolcott-Rallison syndrome, a permanent neonatal diabetes mellitus: about two autopsy cases.
P2860
Q29620447-E777C4BD-BCC8-4B85-963C-7A26AD817D82Q33295459-41F4CB94-DEF1-408A-A4B9-F79CA89002E5Q33500340-A25A5911-B33B-4410-A9D7-8E03342E2310Q34005542-BB77886D-D6AA-4FD0-9EC2-3D6F324132CDQ34024253-7873C842-16B2-49AE-A0F3-318CE4EF92E8Q34148057-BE8EAAFB-76DA-4C2E-B4B7-51251697A268Q34348245-BC3ED82F-B559-45F3-8EDD-B6EE36A74E28Q35055531-5E0EF52C-9242-4020-9099-4E4E9E2722A9Q35184903-AC4519C6-AA53-43AB-9731-27D17DC25672Q35551757-252C4628-EE36-4886-8508-BA8DDB9C35D0Q36132790-5B0CA2B9-AE27-4C3A-8BC6-501F5A89D5B4Q36435206-B28A4E72-6334-4AFA-8DC2-5768023A9A91Q37039560-A518C742-C6B8-4C2D-8678-F13A29146D93Q39142751-52712487-BC8A-4403-95D2-A4AD3FB4CC50Q39259539-6266695B-2DBE-44DE-A09B-C6F86382822BQ39902796-7133D3AE-E412-4DB0-84F6-2006BE3E0677Q40021459-29D54DA5-99E8-4719-852D-197A2999E1C4Q43226732-27DD41BA-AD24-4918-AE71-991836031DBCQ46639276-3FF0C8DA-7D9A-4DC0-8EF6-181D960452F5Q47444302-0F99B64A-BF08-4822-9121-E442158D2EADQ53325918-46F35BF5-23EF-48DF-B999-B8D4D14245E3Q53864041-35485B8A-766E-48BB-830A-FBB89094AB7DQ54329371-EB14B684-C473-46B4-A4E0-33C25A3CE64A
P2860
PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver
description
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im August 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/08/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/08/01)
@nl
наукова стаття, опублікована в серпні 2003
@uk
مقالة علمية (نشرت في أغسطس 2003)
@ar
name
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@ast
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@en
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@nl
type
label
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@ast
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@en
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@nl
prefLabel
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@ast
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@en
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@nl
P2093
P921
P3181
P356
P1433
P1476
PERK eIF2alpha kinase regulate ...... actor-I derived from the liver
@en
P2093
Aryn Gabai
Clifford J. Rosen
Douglas R. Cavener
Frank Zambito
Jeff O'Neil
Kaori Iida
Peichuan Zhang
Sheng'ai Li
Shun-Hsin Liang
P304
P3181
P356
10.1210/EN.2003-0236
P407
P577
2003-08-01T00:00:00Z