The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
about
Iron dysregulation in Huntington's diseaseRhes, a physiologic regulator of sumoylation, enhances cross-sumoylation between the basic sumoylation enzymes E1 and Ubc9.Rhes suppression enhances disease phenotypes in Huntington's disease miceMice lacking rhes show altered morphine analgesia, tolerance, and dependence.Rhes and AGS1/Dexras1 affect signaling by dopamine D1 receptors through adenylyl cyclase.Exploration of sex differences in Rhes effects in dopamine mediated behaviors.Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neuronsRhes: a GTP-binding protein integral to striatal physiology and pathology.Sex differences in novelty- and psychostimulant-induced behaviors of C57BL/6 mice.Effects of the Ras homolog Rhes on Akt/protein kinase B and glycogen synthase kinase 3 phosphorylation in striatum.Ontogeny and dopaminergic regulation in brain of Ras homolog enriched in striatum (Rhes)RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum.Small G Proteins Dexras1 and RHES and Their Role in Pathophysiological Processes.Using the shared genetics of dystonia and ataxia to unravel their pathogenesis.Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.Striatum specific protein, Rhes regulates AKT pathway.PKA modulates iron trafficking in the striatum via small GTPase, Rhes.
P2860
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P2860
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
description
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Oktober 2008 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2008/10/29)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/10/29)
@nl
наукова стаття, опублікована в жовтні 2008
@uk
مقالة علمية (نشرت في 29-10-2008)
@ar
name
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@ast
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@en
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@nl
type
label
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@ast
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@en
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@nl
prefLabel
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@ast
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@en
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@nl
P2093
P2860
P1433
P1476
The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice
@en
P2093
Daniela Spano
Gabriel C. Quintero
Gerald J. Lahoste
Laura M. Harrison
P2860
P304
P356
10.1097/WNR.0B013E3283118434
P577
2008-10-29T00:00:00Z